Shikova E E, Ivanov I G, Mladenov Z M
Institute of General and Comparative Pathology, Bulgarian Academy of Sciences, Sofia, Bulgaria.
J Ultrastruct Mol Struct Res. 1988 Mar;98(3):294-8. doi: 10.1016/s0889-1605(88)80921-2.
Type A oncornavirus-like particles (TAOLP) were found in the cytoplasm of turkey bone marrow cells transformed by strain Mc-31 avian leukemia virus. They resembled morphologically the cores of budding virions and the cores of immature extracellular Mc-31 virus particles. TAOLP were observed more often in T3Mc31 cells where cytopathological changes existed. TAOLP were not found in the materials from in vivo experiments. A relationship is likely to exist between TAOLP and Mc-31 virus and TAOLP could represent a side product of Mc-31 virus replication.
在由Mc-31禽白血病病毒株转化的火鸡骨髓细胞的细胞质中发现了A型肿瘤病毒样颗粒(TAOLP)。它们在形态上类似于出芽病毒粒子的核心以及未成熟细胞外Mc-31病毒粒子的核心。在存在细胞病理变化的T3Mc31细胞中更常观察到TAOLP。在体内实验的材料中未发现TAOLP。TAOLP与Mc-31病毒之间可能存在关联,并且TAOLP可能代表Mc-31病毒复制的副产物。