部分肾切除术与冷冻消融联合治疗在双侧同步性肾细胞癌中实现了良好的癌症控制和肾功能保留。

A Combination Therapy of Partial Nephrectomy and Cryoablation Achieved Good Cancer Control and Renal Function in Bilateral Synchronous Renal Cell Carcinoma.

作者信息

Takamoto Atsushi, Araki Motoo, Wada Koichiro, Sugimoto Morito, Kobayashi Yasuyuki, Sasaki Katsumi, Watanabe Toyohiko, Nasu Yasutomo

机构信息

Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan.

出版信息

Acta Med Okayama. 2017 Apr;71(2):187-190. doi: 10.18926/AMO/54989.

DOI:10.18926/AMO/54989

PMID:28420902

Abstract

We report the case of a 58-year-old Japanese man with bilateral synchronous renal cell carcinoma (RCC). The diameters of the right and left tumors were 56 and 69 mm, respectively. Both tumors were endophytic. Cryoablation with prophylactic embolization was performed for the left tumor, and 1 month later, a right open partial nephrectomy was performed. No recurrence was observed during a 16-month follow-up, and the serum creatinine level has been stable. The prognosis of bilateral synchronous RCC is better than that of dialysis patients. The novel approach of combining cryoablation and partial nephrectomy can achieve good cancer control and renal function in bilateral RCC.

摘要

我们报告了一例58岁的日本男性双侧同步性肾细胞癌（RCC）病例。左右肿瘤直径分别为56毫米和69毫米。两个肿瘤均为内生性。对左侧肿瘤进行了冷冻消融并预防性栓塞，1个月后，对右侧进行了开放性部分肾切除术。在16个月的随访期间未观察到复发，血清肌酐水平一直稳定。双侧同步性RCC的预后优于透析患者。冷冻消融与部分肾切除术相结合的新方法可在双侧RCC中实现良好的癌症控制和肾功能。