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使用基于丝素蛋白纤维的植入物修复空肠壁缺损

Regeneration of jejunal wall defect using an implant based on silk fibroin fibers.

作者信息

Moisenovich M M, Kulikov D A, Goncharenko A V, Arkhipova A Y, Vasiljeva T V, Filyushkin Yu N, Arkhipova L V, Kotlyarova M S, Kulikov A V, Mashkov A E, Agapov I I, Kirpichnikov M P

机构信息

Biological Faculty, Moscow State University, Moscow, 119234, Russia.

Vladimirskii Moscow Regional Research Clinical Institute, Moscow, 129110, Russia.

出版信息

Dokl Biochem Biophys. 2017 Jan;472(1):12-14. doi: 10.1134/S1607672917010045. Epub 2017 Apr 19.

Abstract

Regenerative properties of fibroin implant vitalized with allogeneic bone marrow cells were assessed. The study was performed using the experimental model of rat jejunum wall damage. Three weeks after surgery, we observed recovery of all layers of the jejunum wall at the site of injury and complete degradation of the implant material.

摘要

评估了用同种异体骨髓细胞激活的丝素蛋白植入物的再生特性。该研究采用大鼠空肠壁损伤的实验模型进行。手术后三周,我们观察到损伤部位空肠壁各层的恢复以及植入材料的完全降解。

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