Ye Yanping, Zhu Bo, Jiang Li, Jiang Qi, Wang Meiping, Hua Lin, Xi Xiuming
1Department of Respiratory Medicine, Fu Xing Hospital, Capital Medical University, Beijing, China.2Department of Critical Care Medicine, Fu Xing Hospital, Capital Medical University, Beijing, China.3School of Biomedical Engineering, Capital Medical University, Beijing, China.
Crit Care Med. 2017 Jul;45(7):1160-1167. doi: 10.1097/CCM.0000000000002360.
To evaluate the contemporary practice, outcomes, and costs related to mechanical ventilation among ICUs in China.
A prospective observational cohort study.
Fourteen ICUs among 13 hospitals in Beijing, China.
Seven hundred ninety-three patients who received at least 24 hours of mechanical ventilation within the first 48 hours of ICU stay.
None.
The mean age was 64 years. Sixty-three percent were male. New acute respiratory failure accounted for 85.5% of mechanical ventilation cases. Only 4.7% of the patients received mechanical ventilation for acute exacerbation of chronic obstructive pulmonary disease. The most widely used ventilation mode was the combination of synchronized intermittent mandatory ventilation and pressure support (43.6%). Use of lung-protective ventilation is widespread with tidal volumes of 7.1 mL/kg (2.1 mL/kg). The ICU/hospital mortality was 27.6%/29.3%, respectively (8.5%/9.7% for surgical patients and 41.3%/43.2% for medical patients, respectively). The mean level of ICU/hospital cost per patient was $15,271 (18,940)/$22,946 (25,575), respectively. The mean daily ICU cost per patient was $1,212.
For the first time, we obtained a preliminary epidemiology data of mechanical ventilation in Beijing, China, through the study. Compared with the other nations, our patients are older, predominantly male, and treated according to prevailing international guidelines yet at a relatively high cost and high mortality. The expanding elderly population predicts increase demand for mechanical ventilation that must be met by continuous improvement in quality and efficiency of critical care services.
评估中国重症监护病房(ICU)中与机械通气相关的当代实践、结局及成本。
前瞻性观察性队列研究。
中国北京13家医院中的14个ICU。
793例在入住ICU的前48小时内接受至少24小时机械通气的患者。
无。
平均年龄为64岁。63%为男性。新发性急性呼吸衰竭占机械通气病例的85.5%。仅4.7%的患者因慢性阻塞性肺疾病急性加重接受机械通气。最常用的通气模式是同步间歇指令通气与压力支持相结合(43.6%)。肺保护性通气的使用很普遍,潮气量为7.1 mL/kg(2.1 mL/kg)。ICU/医院死亡率分别为27.6%/29.3%(外科患者为8.5%/9.7%,内科患者为41.3%/43.2%)。每位患者的ICU/医院平均费用水平分别为15,271美元(18,940元人民币)/22,946美元(25,575元人民币)。每位患者每天的ICU平均费用为1,212美元。
通过本研究,我们首次获得了中国北京机械通气的初步流行病学数据。与其他国家相比,我们的患者年龄更大,以男性为主,按照现行国际指南进行治疗,但成本相对较高且死亡率较高。老年人口的不断增加预示着对机械通气的需求将会增加,这必须通过持续提高重症监护服务的质量和效率来满足。