Kobayashi Yasushi
Department of Anatomy and Neurobiology, National Defence Medical College.
Brain Nerve. 2017 Apr;69(4):427-437. doi: 10.11477/mf.1416200760.
The limbic lobe defined by Broca is a cortical region with highly diverse structure and functions, and comprises the paleo-, archi-, and neocortices as well as their transitional zones. In the limbic lobe, Brodmann designated areas 27, 28, 34, 35, and 36 adjacent to the hippocampus, and areas 23, 24, 25, 26, 29, 30, 31, 32, and 33 around the corpus callosum. In the current literature, areas 27 and 28 correspond to the presubiculum and entorhinal cortex, respectively. Area 34 represents the cortico-medial part of the amygdaloid complex. Areas 35 and 36 roughly cover the perirhinal and parahippocampal cortices. Areas 24, 25, 32, and 33 belong to the anterior cingulate gyrus, while areas 23, 26, 29, 30, and 31 to the posterior cingulate gyrus. Areas 25, 32, and the anteroinferior portion of area 24 are deeply involved in emotional responses, particularly in their autonomic functions, through reciprocal connections with the amygdaloid complex, anterior thalamus and projections to the brainstem and spinal visceral centers. Areas 29 and 30 have dense reciprocal connections with areas 23 and 31, the dorsolateral prefrontal areas, and the regions related to the hippocampus. They play pivotal roles in mediating spatial cognition, working memory processing, and episodic memory formation.
由布罗卡定义的边缘叶是一个结构和功能高度多样的皮质区域，包括古皮质、旧皮质和新皮质及其过渡区。在边缘叶中，布罗德曼将与海马体相邻的27、28、34、35和36区，以及胼胝体周围的23、24、25、26、29、30、31、32和33区进行了划分。在当前文献中，27区和28区分别对应于前扣带回和内嗅皮质。34区代表杏仁复合体的皮质内侧部分。35区和36区大致覆盖了嗅周皮质和海马旁皮质。24、25、32和33区属于前扣带回，而23、26、29、30和31区属于后扣带回。25、32区以及24区的前下部通过与杏仁复合体、丘脑前部的相互连接以及向脑干和脊髓内脏中枢的投射，深度参与情绪反应，尤其是自主神经功能。29区和30区与23区和31区、背外侧前额叶区域以及与海马体相关的区域有密集的相互连接。它们在介导空间认知、工作记忆处理和情景记忆形成中起关键作用。
