Nkrumah F K, Pizza G, Neequaye J, Viza D, De Vinci C, Levine P H
Burkitt Tumour Project, Univ. of Ghana Medical Sch. Accra.
J Exp Pathol. 1987 Summer;3(4):463-9.
Twenty-two African children with endemic Burkitt's lymphoma entered a study to evaluate the possible efficacy of a transfer factor (TF) with specific activity against Eptein-Barr virus in preventing disease relapses. Five of eleven patients have so far relapsed in the non TF-treated group as against two of eleven in the TF-treated group. The patterns of relapse and observable increased disease free remission duration in the TF-treated group strongly suggest a beneficial effect particularly in the prevention of late relapses. A larger series of patients treated with this specific TF are needed to confirm these observations in endemic Burkitt's lymphoma.
22名患有地方性伯基特淋巴瘤的非洲儿童参与了一项研究，以评估一种对爱泼斯坦-巴尔病毒具有特异性活性的转移因子（TF）在预防疾病复发方面的潜在疗效。截至目前，在未接受TF治疗的组中，11名患者中有5人复发，而在接受TF治疗的组中，11名患者中有2人复发。TF治疗组的复发模式以及可观察到的无病缓解期延长有力地表明了其有益效果，特别是在预防晚期复发方面。需要对更多使用这种特异性TF治疗的患者进行研究，以证实这些在地方性伯基特淋巴瘤中的观察结果。
