Wada Kara J, Calhoun Karen H
Division of Allergy, Department of Otolaryngology Head & Neck Surgery, The Ohio State University Wexner School of Medicine, Columbus, Ohio, USA.
Curr Opin Otolaryngol Head Neck Surg. 2017 Jun;25(3):252-254. doi: 10.1097/MOO.0000000000000364.
The purpose of this review is to improve otolaryngologists' antibiotic stewardship by detailing current approaches to penicillin allergy.
Although up to 15% of hospitalized patients in the United States have a penicillin allergy recorded on their charts, fewer than 10% of these have a true penicillin allergy.
Using a combination of a detailed allergy history, skin testing and graded-dose administration, many patients whose charts say 'penicillin-allergic' can safely be treated with penicillin and cross-reacting antibiotics. This permits use of narrower-spectrum antibiotics and saves money.
本综述的目的是通过详细阐述当前针对青霉素过敏的处理方法，来改善耳鼻喉科医生的抗生素管理。
尽管在美国有多达15%的住院患者在病历上记录有青霉素过敏，但其中真正对青霉素过敏的不到10%。
通过结合详细的过敏史、皮肤试验和分级剂量给药，许多病历显示“青霉素过敏”的患者可以安全地使用青霉素和交叉反应性抗生素进行治疗。这使得可以使用窄谱抗生素并节省费用。
