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[人乳头瘤病毒疫苗接种:意大利某地区的主动推广]

[HPV vaccination: active offer in an Italian region].

作者信息

Terracciano Elisa, D'Alò Gian Loreto, Aquilani Silvia, Aversa Anna Maria, Bartolomei Giuseppina, Calenda Maria Gabriella, Catapano Raffaele, Compagno Silvio, Della Rovere Piera, Fraioli Angelo, Ieraci Roberto, Reggiani Daniela, Sgricia Stefano, Spadea Antonietta, Zaratti Laura, Franco Elisabetta

机构信息

Scuola di Specializzazione in Igiene e Medicina Preventiva, Università degli Studi di Roma Tor Vergata, Roma, Italia.

ASL Viterbo, Italia.

出版信息

Ig Sanita Pubbl. 2017 Jan-Feb;73(1):77-94.

PMID:28428646
Abstract

Human Papillomavirus is responsible for 4.8% of cancers, and is the main cause of cervical cancer. Cervical cancer can be reduced by mean of secondary prevention (PAP-test, HPV-DNA test), while through primary prevention (anti-HPV vaccine) the incidence of other HPV-attributable cancers can also be reduced. In Italy, anti-HPV vaccination is part of the immunization schedule in girls since 2008, and in 2017 it was extended to boys. However, vaccine coverage is decreasing nationwide. This study aims to examine anti-HPV vaccination practices in Health care services of Lazio Region, Italy. Questionnaires were sent or administered directly to those in charge of vaccinations. Data, collected from 11/12 (92%) Lazio Local Health Units and from 116 vaccination centers, show a remarkable diversity in the offer: 41% of the centers open only 1-2 days/week, 42% only in the morning, and only 7% are open on Saturday. Vaccination is available by reservation only in 62% of the centers, while vaccines are not administered to ≥18 years subjects in 33%; 93% of the centers call actively the girls in the target cohort, while 70% and 94% recall the patients who had not received the first or the second dose of vaccine, respectively. Collaboration with family physicians and/or pediatricians was declared by 80% of the centers. Vaccine coverage could probably be improved by addressing the highlighted critical issues and applying best practices widely.

摘要

人乳头瘤病毒导致了4.8%的癌症,是宫颈癌的主要病因。宫颈癌可通过二级预防(巴氏试验、人乳头瘤病毒DNA检测)来降低,而通过一级预防(抗人乳头瘤病毒疫苗),其他与人乳头瘤病毒相关的癌症发病率也可降低。在意大利,自2008年起,抗人乳头瘤病毒疫苗接种成为女孩免疫计划的一部分,2017年该计划扩大至男孩。然而,全国范围内的疫苗接种覆盖率正在下降。本研究旨在调查意大利拉齐奥地区医疗服务中的抗人乳头瘤病毒疫苗接种情况。问卷直接发送或发放给负责疫苗接种的人员。从拉齐奥地区11/12(92%)的地方卫生单位和116个疫苗接种中心收集的数据显示,疫苗接种服务存在显著差异:41%的中心每周仅开放1 - 2天,42%仅在上午开放,只有7%在周六开放。62%的中心仅接受预约接种,33%的中心不给18岁及以上人群接种疫苗;93%的中心主动联系目标队列中的女孩,70%和94%的中心分别召回未接种第一剂或第二剂疫苗的患者。80%的中心宣称与家庭医生和/或儿科医生有合作。通过解决突出的关键问题并广泛应用最佳实践,疫苗接种覆盖率可能会得到提高。

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