[使用动脉内导管对不可切除肝细胞癌进行动脉灌注化疗和栓塞]
[Arterial infusion chemotherapy and embolization in unresectable hepatocellular carcinoma using an intraarterial catheter].
作者信息
Tanada M, Soga H, Kurita K, Takiyama W, Saeki H, Takashima S, Satoh G, Wada T, Jinno K, Tokuyama K
机构信息
Dept. of Surgery, Shikoku National Cancer Center Hospital.
出版信息
Gan To Kagaku Ryoho. 1988 Aug;15(8 Pt 2):2470-2.
We performed arterial infusion chemotherapy and embolization on 22 patients with unresectable hepatocellular carcinoma via an intraarterial catheter, which was inserted in the hepatic artery under laparotomy. The administration frequency of intraarterial chemotherapy on a patient was 1 to 155 with a median of 17, while that of embolization was 1 to 6 with a median of 2.5. The maximal and average durations of a catheter in place were 15 and 4 months, respectively. The survival rates were 50% in one year, 18% in two years, and 12% in three years. Insertion technique and management of the catheter are relatively safe and easy, so catheterization of the hepatic artery would enable us to develop new treatment modalities.
我们通过在剖腹手术中插入肝动脉的动脉内导管，对22例无法切除的肝细胞癌患者进行了动脉灌注化疗和栓塞治疗。患者动脉内化疗的给药频率为1至155次，中位数为17次，而栓塞治疗的给药频率为1至6次，中位数为2.5次。导管在位的最长和平均时间分别为15个月和4个月。一年生存率为50%，两年生存率为18%，三年生存率为12%。导管的插入技术和管理相对安全且简便，因此肝动脉插管将使我们能够开发新的治疗方式。
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