Arai K, Matsui O, Takashima T, Kadoya M, Yoshikawa J, Gabata T, Ueda K, Kawamori Y, Izumi R, Kobayashi K
Department of Radiology, School of Medicine, Kanazawa University, Japan.
Radiat Med. 1990 Sep-Oct;8(5):191-8.
A total of 155 cases of hepatocellular carcinoma smaller than 3 cm in greatest diameter were studied, and the survival rates obtained with various treatment methods were calculated. Patients were divided into an operated group (72 cases), transcatheter arterial embolization (TAE) group (52 cases), percutaneous ethanol injection therapy (PEIT) group (five cases), and a miscellaneous group (26 cases) according to the treatment received. The miscellaneous group included intraarterial chemotherapy, systemic chemotherapy, and no therapy. The survival rates of the operated and TAE groups were significantly higher than those of the miscellaneous group, but the survival rates of the TAE group decreased after two years had passed, and TAE showed limited long-term survival. In the PEIT group, the survival rates after three years were higher than those of the TAE group. TAE is effective for inoperable small HCC, but the indications for PEIT should be considered actively.
共研究了155例最大直径小于3cm的肝细胞癌患者，并计算了采用各种治疗方法所获得的生存率。根据接受的治疗方法，患者被分为手术组（72例）、经导管动脉栓塞术（TAE）组（52例）、经皮乙醇注射治疗（PEIT）组（5例）和其他组（26例）。其他组包括动脉内化疗、全身化疗和未治疗。手术组和TAE组的生存率显著高于其他组，但TAE组在两年后生存率下降，且TAE显示长期生存率有限。在PEIT组中，三年后的生存率高于TAE组。TAE对无法手术的小肝癌有效，但应积极考虑PEIT的适应证。
