Stachon Peter, Kalbhenn Johannes, Walterspacher Stephan, Bode Christoph, Staudacher Dawid
Klinik für Kardiologie und Angiologie I, Universitäts-Herzzentrum Freiburg-Bad Krozingen.
Klinik für Anästhesiologie und Intensivmedizin, Universitätsklinikum Freiburg.
Dtsch Med Wochenschr. 2017 Apr;142(8):596-600. doi: 10.1055/s-0043-101530. Epub 2017 Apr 21.
Drowning with submersion over 10 minutes is associated with a high mortality. Here, we present a case, in which a good neurological outcome was achieved after interdisciplinary, intensive care therapy despite submersion of 20 minutes followed by 16 hours of hypoxia. A 19 year old man drowned in fresh-water. After 20 minutes submersion he was localized and salvaged from 8 meters depth and primarily resuscitated successfully after 10 minutes. Within the next hour, there condition worsened by respiratory deterioration due to a massive capillary leak syndrome in addition to a disseminated intravascular coagulation. This made implantation of a veno-venous ECMO (extracorporeal membrane oxygenation) therapy necessary. Despite intensive care medicine including extracorporeal therapy a sufficient oxygenation (arterial pO > 60 mmHg) was reached only 16 hours after the drowning. During this time the patient was treated with a mild therapeutic hypothermia for cerebral protection. Despite the prolonged hypoxia, ECMO could be removed five days after the drowning and the patient was extubated after another five days without significant neurological deficits. Despite submersion of 20 minutes followed by prolonged hypoxia, a good neurological outcome could be achieved in our patient. This case suggests, that tolerance of hypoxia is possibly underestimated after drowning.
淹没超过10分钟的溺水与高死亡率相关。在此,我们报告一例病例,尽管患者被淹没20分钟并伴有16小时的缺氧,但经过多学科的重症监护治疗后仍取得了良好的神经学预后。一名19岁男性在淡水中溺水。被淹没20分钟后,他在8米深的水中被找到并打捞上岸,10分钟后初步复苏成功。在接下来的一小时内,除了弥散性血管内凝血外,由于大量毛细血管渗漏综合征导致呼吸恶化,其病情进一步加重。这使得有必要植入静脉-静脉体外膜肺氧合(ECMO)进行治疗。尽管采取了包括体外治疗在内的重症监护措施,但直到溺水后16小时才实现充分氧合(动脉血氧分压>60mmHg)。在此期间,为保护大脑对患者进行了轻度治疗性低温。尽管缺氧时间延长,但在溺水五天后可撤除ECMO,再过五天患者拔管,且无明显神经功能缺损。尽管患者被淹没20分钟并伴有长时间缺氧,但仍取得了良好的神经学预后。该病例表明,溺水后对缺氧的耐受性可能被低估了。