Pupek Alex, Matthewson Beverly, Whitman Erin, Fullarton Rachel, Chen Yu
.Department of Laboratory Medicine, Dr. Everett Chalmers Regional Hospital, Horizon Health Network Fredericton, NB, Canada; and Dalhousie Medical Program in New Brunswick, Saint John, NB, Canada.
Department of Laboratory Medicine, Dr. Everett Chalmers Regional Hospital, Horizon Health Network, Fredericton, NB, Canada.
Clin Chem Lab Med. 2017 Aug 28;55(10):1537-1544. doi: 10.1515/cclm-2016-1157.
The pneumatic tube system (PTS) is commonly used in modern clinical laboratories to provide quick specimen delivery. However, its impact on sample integrity and laboratory testing results are still debatable. In addition, each PTS installation and configuration is unique to its institution. We sought to validate our Swisslog PTS by comparing routine chemistry, hematology, coagulation and blood gas test results and sample integrity indices between duplicate samples transported either manually or by PTS.
Duplicate samples were delivered to the core laboratory manually by human courier or via the Swisslog PTS. Head-to-head comparisons of 48 routine chemistry, hematology, coagulation and blood gas laboratory tests, and three sample integrity indices were conducted on 41 healthy volunteers and 61 adult patients.
The PTS showed no impact on sample hemolysis, lipemia, or icterus indices (all p<0.05). Although alkaline phosphatase, total bilirubin and hemoglobin reached statistical significance (p=0.009, 0.027 and 0.012, respectively), all had very low average bias which ranged from 0.01% to 2%. Potassium, total hemoglobin and percent deoxyhemoglobin were statistically significant for the neonatal capillary tube study (p=0.011, 0.033 and 0.041, respectively) but no biases greater than ±4% were identified for these parameters. All observed differences of these 48 laboratory tests were not clinically significant.
The modern PTS investigated in this study is acceptable for reliable sample delivery for routine chemistry, hematology, coagulation and blood gas (in syringe and capillary tube) laboratory tests.
气动管道系统（PTS）在现代临床实验室中常用于快速运送标本。然而，其对样本完整性和实验室检测结果的影响仍存在争议。此外，每个PTS装置和配置在其机构中都是独特的。我们试图通过比较手动或通过PTS运送的重复样本之间的常规化学、血液学、凝血和血气检测结果以及样本完整性指标，来验证我们的瑞仕格PTS。
重复样本由专人手动或通过瑞仕格PTS送至核心实验室。对41名健康志愿者和61名成年患者进行了48项常规化学、血液学、凝血和血气实验室检测以及三项样本完整性指标的直接比较。
PTS对样本溶血、脂血或黄疸指数均无影响（所有p<0.05）。尽管碱性磷酸酶、总胆红素和血红蛋白达到统计学显著性（分别为p=0.009、0.027和0.012），但所有这些指标的平均偏差都非常低，范围为0.01%至2%。在新生儿毛细管研究中，钾、总血红蛋白和脱氧血红蛋白百分比具有统计学显著性（分别为p=0.011、0.033和0.041），但这些参数的偏差均未超过±4%。这48项实验室检测中观察到的所有差异在临床上均无显著意义。
本研究中所调查的现代PTS可用于常规化学、血液学、凝血和血气（注射器和毛细管）实验室检测的可靠样本运送。
