Walshe John M
Formerly of Addenbrookes Hospital, Cambridge and the Middlesex Hospital, London, UK.
Handb Clin Neurol. 2017;142:1-5. doi: 10.1016/B978-0-444-63625-6.00001-X.
This chapter focuses on the historic aspects of the development of much of our current knowledge of the diagnosis and treatment of Wilson disease. Included are descriptions of the clinical signs of neurologic and hepatic disease, the natural history of disease progression, studies of disease pathogenesis and a unique perspective on the development of diagnostic testing and pharmacological therapy.
本章重点关注我们目前对威尔逊病诊断和治疗的许多知识发展的历史方面。内容包括神经和肝脏疾病的临床体征描述、疾病进展的自然史、疾病发病机制研究以及诊断测试和药物治疗发展的独特视角。
