Liu G J, Liu C Z, Xiao Z Q
First Hospital, Kunming Medical College.
Zhonghua Zhong Liu Za Zhi. 1988 Jan;10(1):48-50.
Long-term result of 61 patients with primary lung cancer treated by pneumonectomy is reported. There were 55 males and 6 females. The ages ranged from 23 to 62 years with a mean of 47.7. Of these 61 patients, 49 died within ten years after pneumonectomy, 34 of them died of recurrence or metastasis and 8 of cardio-pulmonary diseases. The 5 and 10 year survival rates were 24.1% and 16%, significantly lower than those of 104 patients treated by lobectomy during the same period (42.6% and 33.3%), P less than 0.05). The 5 and 10 year survival rates of left pneumonectomy were statistically higher than those of right pneumonectomy (36.7% and 21.7% versus 8.3% and 9.5%, P less than 0.05). In this paper, the dissection of mediastinal lymph nodes and effect on postoperative cardiopulmonary functions are discussed. The postoperative radiotherapy, to the mediastinum, is advocated because thorough dissection of the mediastinal lymph nodes is very difficult. Sleeve-lobectomy instead of pneumonectomy is indicated for those patients with the tumor located in one lobe and the main bronchus involved.
报告了61例接受肺切除术治疗的原发性肺癌患者的长期结果。其中男性55例，女性6例。年龄范围为23至62岁，平均47.7岁。这61例患者中，49例在肺切除术后10年内死亡，其中34例死于复发或转移，8例死于心肺疾病。5年和10年生存率分别为24.1%和16%，显著低于同期接受肺叶切除术的104例患者（42.6%和33.3%），P<0.05）。左肺切除术的5年和10年生存率在统计学上高于右肺切除术（36.7%和21.7%对8.3%和9.5%，P<0.05）。本文讨论了纵隔淋巴结清扫及其对术后心肺功能的影响。由于纵隔淋巴结的彻底清扫非常困难，因此主张对纵隔进行术后放疗。对于肿瘤位于一叶且累及主支气管的患者，建议行袖状肺叶切除术而非肺切除术。
