对结直肠癌患者心理社会干预措施的系统评价。
A systematic review of psychosocial interventions for colorectal cancer patients.
作者信息
Mosher Catherine E, Winger Joseph G, Given Barbara A, Shahda Safi, Helft Paul R
机构信息
Department of Psychology, Indiana University-Purdue University Indianapolis, 402 North Blackford Street, LD 124, Indianapolis, IN, 46202, USA.
College of Nursing, Michigan State University, 355 Bogue St., Room #C383, East Lansing, MI, 48824, USA.
出版信息
Support Care Cancer. 2017 Jul;25(7):2349-2362. doi: 10.1007/s00520-017-3693-9. Epub 2017 Apr 22.
PURPOSE
A significant minority of colorectal cancer (CRC) patients experience clinically meaningful distress that may warrant intervention. The goal of this systematic review was to assess the impact of psychosocial interventions on quality-of-life and psychosocial outcomes for CRC patients.
METHODS
A systematic search of CINAHL, MEDLINE, PsycINFO, and PsycARTICLES was undertaken to obtain relevant randomized controlled trials (RCTs) published through October 2016.
RESULTS
Fourteen RCTs of psychosocial interventions for CRC patients were identified. Only three of these RCTs showed significant intervention effects on multiple mental health outcomes. These interventions included written and verbal emotional expression, progressive muscle relaxation training, and a self-efficacy enhancing intervention. Eight of the 14 trials, testing a range of psychoeducational and supportive care interventions, produced little to no effects on study outcomes. An evaluation of RCT quality highlighted the need for greater rigor in study methods and reporting.
CONCLUSION
A limited evidence base supports the efficacy of psychosocial interventions for CRC patients. Large-scale trials are needed before drawing definitive conclusions regarding intervention impact.
目的
相当一部分结直肠癌（CRC）患者经历了具有临床意义的痛苦，可能需要进行干预。本系统评价的目的是评估心理社会干预对CRC患者生活质量和心理社会结局的影响。
方法
对CINAHL、MEDLINE、PsycINFO和PsycARTICLES进行系统检索，以获取截至2016年10月发表的相关随机对照试验（RCT）。
结果
确定了14项针对CRC患者的心理社会干预随机对照试验。其中只有3项随机对照试验对多种心理健康结局显示出显著的干预效果。这些干预措施包括书面和口头情绪表达、渐进性肌肉松弛训练以及自我效能增强干预。14项试验中的8项，测试了一系列心理教育和支持性护理干预措施，对研究结局几乎没有影响。对随机对照试验质量的评估强调了在研究方法和报告方面需要更加严格。
结论
有限的证据支持心理社会干预对CRC患者的疗效。在就干预影响得出明确结论之前，需要进行大规模试验。
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