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颅内动脉瘤性蛛网膜下腔出血

Aneurysmal Subarachnoid Hemorrhage.

机构信息

Department of Neurosurgery, Düsseldorf University Hospital; Department of Diagnostic and Interventional Radiology, Düsseldorf University Hospital; Department of Diagnostic and Interventional Radiology, Düsseldorf University Hospital.

出版信息

Dtsch Arztebl Int. 2017 Mar 31;114(13):226-236. doi: 10.3238/arztebl.2017.0226.

Abstract

BACKGROUND

Aneurysmal subarachnoid hemorrhage (SAH) is associated with a mortality of more than 30%. Only about 30% of patients with SAB recover sufficiently to return to independent living.

METHODS

This article is based on a selective review of pertinent literature retrieved by a PubMed search.

RESULTS

Acute, severe headache, typically described as the worst headache of the patient's life, and meningismus are the characteristic manifestations of SAH. Computed tomog raphy (CT) reveals blood in the basal cisterns in the first 12 hours after SAH with approximately 95% sensitivity and specificity. If no blood is seen on CT, a lumbar puncture must be performed to confirm or rule out the diagnosis of SAH. All patients need intensive care so that rebleeding can be avoided and the sequelae of the initial bleed can be minimized. The immediate transfer of patients with acute SAH to a specialized center is crucially important for their outcome. In such centers, cerebral aneurysms can be excluded from the circulation either with an interventional endovascular procedure (coiling) or by microneurosurgery (clipping).

CONCLUSION

SAH is a life-threatening condition that requires immediate diagnosis, transfer to a neurovascular center, and treatment without delay.

摘要

背景

颅内动脉瘤性蛛网膜下腔出血(SAH)的死亡率超过 30%。仅有约 30%的患者能够充分恢复并回归独立生活。

方法

本文基于对通过 PubMed 搜索获得的相关文献的选择性回顾。

结果

SAH 的特征性表现是急性、剧烈头痛,通常被描述为患者一生中最严重的头痛,以及脑膜刺激征。发病后 12 小时内的 CT 可发现基底池有血液,其敏感性和特异性均约为 95%。如果 CT 未见出血,必须进行腰椎穿刺以确认或排除 SAH 的诊断。所有患者均需进行重症监护,以避免再出血并使初始出血的后遗症最小化。将急性 SAH 患者立即转至专门中心对其预后至关重要。在这些中心,可以通过介入性血管内治疗(线圈栓塞)或显微镜神经外科手术(夹闭)将脑动脉瘤从循环中排除。

结论

SAH 是一种危及生命的疾病,需要立即诊断、转至神经血管中心,并立即进行治疗。

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