Respiratory Failure Unit, G. Papanikolaou Hospital, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Respiratory Failure Unit, G. Papanikolaou Hospital, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
J Infect Public Health. 2018 Jan-Feb;11(1):133-135. doi: 10.1016/j.jiph.2017.03.004. Epub 2017 Apr 20.
Severe leptospirosis can be a rare cause of acute respiratory distress syndrome (ARDS) and multiorgan failure. A patient who made an impact on how I practice was a case of severe leptospirosis (Weil's disease) that presented as ARDS in the ICU. Leptospirosis is an under-reported infectious disease worldwide and should be considered as a cause of ARDS especially in patients with exposure history complicated with diffuse alveolar bleeding (DAH), icteric hepatitis and renal deterioration. Empiric treatment should be recommended before confirmation of laboratory tests as serological diagnosis is time consuming.
严重的钩端螺旋体病可能是急性呼吸窘迫综合征(ARDS)和多器官衰竭的罕见病因。有一个病例对我的临床实践产生了深远的影响,一位重症钩端螺旋体病(韦尔氏病)患者在 ICU 表现为 ARDS。钩端螺旋体病是一种在全球范围内报告不足的传染病,应将其视为 ARDS 的病因之一,特别是在有接触史且伴有弥漫性肺泡出血(DAH)、黄疸性肝炎和肾功能恶化的患者中。在实验室检测结果确认之前,应推荐经验性治疗,因为血清学诊断耗时较长。