Martin-Granizo Rafael, Garcia-Rielo José Ma, De la Sen Oscar, Maniegas Lourdes, Berguer Alberto, De Pedro Manuel
Department of Oral & Maxillofacial Surgery, Hospital Clinico San Carlos, C/ Prof. Martin Lagos s/n, 28040, Madrid, Spain.
Department of Oral & Maxillofacial Surgery, Hospital Clinico San Carlos, C/ Prof. Martin Lagos s/n, 28040, Madrid, Spain.
J Craniomaxillofac Surg. 2017 Jun;45(6):839-844. doi: 10.1016/j.jcms.2017.03.004. Epub 2017 Mar 24.
To analyse the correlation between the level of activity measured in the single photon emission computed tomography (SPECT) and the pathological findings in patients with condylar hyperplasia (CH).
All patients evaluated in our department between 2007 and 2014 with a diagnosis of condylar hyperplasia who had undergone SPECT, evidenced signs of activity, and had undergone surgery were included. We included 28 patients, of whom 20 were women and 8 men.
The male:female ratio was 2,5:1. The mean age of the subjects was 24.4 years at the time of diagnosis (with a range between 14 and 42 years). In 19 cases the affected condyle was the right, and in the remaining 9 it was the left (ratio R:L 2,1:1). On the SPECT, in 16 patients a high level of activity was identified (57.1%) and in the remaining 12 a low level (42.9%). Only 13 patients (6 in the low-activity group and 7 in the high-activity group) presented with islands of cartilage. When comparing the results between the two groups, the main differences were observed in the parameters related to the islands of cartilage. These were more frequent in the group with high activity compared with low activity (5.5 versus 0 per mm of median). Besides being more frequent, these islands were larger (more than double) in the high-activity group (385.1 μm versus 169.7 μm of median). This is the only statistically significant difference found, a fact that can be explained by the small sample size in the study.
Radioisotope tests are the best indicator of the level of activity in condylar hyperplasia, which seems to be directly related to the intensity signal collection.
分析单光子发射计算机断层扫描(SPECT)测量的活动水平与髁突增生(CH)患者病理结果之间的相关性。
纳入2007年至2014年间在我院接受评估、诊断为髁突增生、接受过SPECT检查、有活动迹象且接受过手术的所有患者。我们纳入了28例患者,其中20例为女性,8例为男性。
男女比例为2.5:1。诊断时受试者的平均年龄为24.4岁(范围在14至42岁之间)。19例患侧髁突为右侧,其余9例为左侧(右:左比例为2.1:1)。在SPECT检查中,16例患者(57.1%)显示高水平活动,其余12例(42.9%)为低水平活动。只有13例患者(低活动组6例,高活动组7例)出现软骨岛。比较两组结果时,在与软骨岛相关的参数上观察到主要差异。与低活动组相比,高活动组中软骨岛更常见(每毫米中位数分别为5.5个和0个)。除了更常见外,这些软骨岛在高活动组中更大(中位数超过两倍)(385.1μm对169.7μm)。这是唯一发现的具有统计学意义差异,这一事实可由研究中的小样本量来解释。
放射性同位素检查是髁突增生活动水平的最佳指标,其似乎与强度信号采集直接相关。