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[高原缺氧对孕期胎儿发育的影响及原因分析]

[Effect of high altitude hypoxia on fetal development during pregnancy and the reason analysis].

作者信息

Liu Juan-Li, Ma Si-Qing, Wuren Ta-Na

机构信息

Department of Critical Care Medicine, Qinghai Provincial People's Hospital, Xining 810007, China.

Plateau Medical Center of Qinghai University, Xining 810001, China.

出版信息

Sheng Li Xue Bao. 2017 Apr 25;69(2):235-239.

Abstract

High altitude hypoxia is an important factor to affect fetal development during pregnancy. In the special environment, maternal physiological functions are regulated to maintain the maternal and fetal homeostasis, so that limited oxygen is to meet the needs of fetal growth and development. In this review, the literatures about the effects of hypoxic environment on fetal development during pregnancy in recent years were summarized, in which the fetal growth characteristics, maternal physiological regulation, genetic and placental influencing factors in high altitude areas were involved. This may be helpful for the reproductive healthcare of women in high altitude region, and also for the treatment and prevention of fetal growth retardation in the hypoxic environment.

摘要

高原缺氧是影响孕期胎儿发育的重要因素。在这一特殊环境中,母体生理功能会进行调节以维持母婴内环境稳定,从而使有限的氧气能够满足胎儿生长发育的需求。本文综述了近年来关于孕期缺氧环境对胎儿发育影响的文献,涉及高原地区胎儿生长特征、母体生理调节、遗传及胎盘影响因素等。这可能有助于高原地区女性的生殖保健,也有助于缺氧环境下胎儿生长受限的治疗与预防。

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