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碘131联合射频消融治疗儿童甲状腺功能亢进性甲状腺肿1例报告

[Iodine 131 joint radio frequency ablation treatment for child with hyperthyroidism goiter: one case report].

作者信息

Chen Yonghua, Liang Li, Fang Yanlan, Wang Chunlin, Li Linfa, Jiang Tian'an

机构信息

Department of Pediatrics, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.

Department of Nuclear Medicine, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.

出版信息

Zhejiang Da Xue Xue Bao Yi Xue Ban. 2017 Jan 25;46(1):89-91. doi: 10.3785/j.issn.1008-9292.2017.02.13.

DOI:10.3785/j.issn.1008-9292.2017.02.13
PMID:28436636
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10396889/
Abstract

A 12-year-old girl presented with a history of cervical mass, and one week of throat discomfort and dyspnea. Five years ago, the patient was diagnosed as Hashimoto's thyroiditis and hyperthyroidism; she received antithyroid drug treatment, but the result was not satisfactory. B-ultrasonic showed that the size of thyroid gland was 8.1 cm×3.2 cm in the left and 8.2 cm×4.8 cm in the right. After iodine 131 combined with radiofrequency ablation (RFA) treatment, throat discomfort and recumbent breathing difficulties disappeared, and B-ultrasonic showed that the size of thyroid reduced to 2.3 cm×1.7 cm (left) and 2.8 cm×2.0 cm (right). No recurrence was observed during the two and a half years of follow-up.

摘要

一名12岁女孩,有颈部肿块病史,伴有一周的咽喉不适和呼吸困难。五年前,该患者被诊断为桥本甲状腺炎和甲状腺功能亢进;她接受了抗甲状腺药物治疗,但效果不佳。B超显示甲状腺大小左侧为8.1 cm×3.2 cm,右侧为8.2 cm×4.8 cm。经碘131联合射频消融(RFA)治疗后,咽喉不适和平卧呼吸困难消失,B超显示甲状腺大小缩小至左侧2.3 cm×1.7 cm,右侧2.8 cm×2.0 cm。随访两年半期间未观察到复发。

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Diagnosis and treatment of Graves' disease with particular emphasis on appropriate techniques in nuclear medicine. General state of knowledge.格雷夫斯病的诊断与治疗,特别强调核医学中的适当技术。知识概况。
Nucl Med Rev Cent East Eur. 2015;18(2):110-6. doi: 10.5603/NMR.2015.0026.
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Graves disease in children: thyroid-stimulating hormone receptor antibodies as remission markers.儿童格雷夫斯病:促甲状腺激素受体抗体作为缓解标志物。
J Pediatr. 2014 May;164(5):1189-1194.e1. doi: 10.1016/j.jpeds.2013.12.047. Epub 2014 Feb 8.
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Single-session treatment of benign cystic thyroid nodules with ethanol versus radiofrequency ablation: a prospective randomized study.乙醇与射频消融治疗良性囊性甲状腺结节:一项前瞻性随机研究。
Radiology. 2013 Oct;269(1):293-300. doi: 10.1148/radiol.13122134. Epub 2013 Apr 24.
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Positive impact of long-term antithyroid drug treatment on the outcome of children with Graves' disease: national long-term cohort study.长期抗甲状腺药物治疗对 Graves 病患儿结局的积极影响:全国性长期队列研究。
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