Kimura Hiroaki, Shikata Jitsuhiko, Odate Seiichi, Soeda Tsunemitsu
Department of Orthopedic Surgery, Gakkentoshi Hospital, Kyoto, Japan.
Clin Spine Surg. 2017 May;30(4):169-175. doi: 10.1097/BSD.0000000000000040.
A single-center case-referent study.
To assess whether the "pedicle screw (PS) fluid sign" on magnetic resonance imaging (MRI) can be used to diagnose deep surgical site infection (SSI) after posterior spinal instrumentation (PSI).
MRI is a useful tool for the early diagnosis of a deep SSI. However, the diagnosis is frequently difficult with feverish patients with clear wounds after PSI because of artifacts from the metallic implants. There are no reports on MRI findings that are specific to a deep SSI after PSI. We found that fluid collection outside the head of the PS on an axial MRI scan (PS fluid sign) strongly suggested the possibility of an abscess.
The SSI group comprised 17 patients with a deep SSI after posterior lumbar spinal instrumentation who had undergone an MRI examination at the onset of the SSI. The non-SSI group comprised 64 patients who had undergone posterior lumbar spinal instrumentation who did not develop an SSI and had an MRI examination within 4 weeks after surgery. The frequency of a positive PS fluid sign was compared between both groups.
The PS fluid sign had a sensitivity of 88.2%, specificity of 89.1%, positive predictive value of 68.1%, and negative predictive value of 96.6%. The 2 patients with a false-negative PS fluid sign in the SSI group had an infection at the disk into which the interbody cage had been inserted. Three of the 7 patients with a false-positive PS fluid sign in the non-SSI group had a dural tear during surgery.
The PS fluid sign is a valuable tool for the early diagnosis of a deep SSI. The PS fluid sign is especially useful for diagnosing a deep SSI in difficult cases, such as feverish patients without wound discharge.
单中心病例对照研究。
评估磁共振成像(MRI)上的“椎弓根螺钉(PS)液体征”是否可用于诊断后路脊柱内固定术(PSI)后深部手术部位感染(SSI)。
MRI是早期诊断深部SSI的有用工具。然而,对于PSI术后伤口清洁但发热的患者,由于金属植入物产生的伪影,诊断常常困难。目前尚无关于PSI后深部SSI特异性MRI表现的报道。我们发现,轴向MRI扫描显示PS头部外侧有液体聚集(PS液体征)强烈提示脓肿的可能性。
SSI组包括17例后路腰椎脊柱内固定术后发生深部SSI且在SSI发病时接受MRI检查的患者。非SSI组包括64例接受后路腰椎脊柱内固定术且未发生SSI并在术后4周内接受MRI检查的患者。比较两组中PS液体征阳性的频率。
PS液体征的灵敏度为88.2%,特异度为89.1%,阳性预测值为68.1%,阴性预测值为96.6%。SSI组中2例PS液体征假阴性的患者在椎间融合器植入的椎间盘处发生感染。非SSI组中7例PS液体征假阳性的患者中有3例在手术中发生硬膜撕裂。
PS液体征是早期诊断深部SSI的有价值工具。PS液体征对于诊断困难病例(如无伤口引流的发热患者)中的深部SSI特别有用。