Sakaura Hironobu, Miwa Toshitada, Yamashita Tomoya, Kuroda Yusuke, Ohwada Tetsuo
Department of Orthopaedic Surgery, Kansai Rosai Hospital, Amagasaki, Hyogo; and.
Department of Orthopaedic Surgery, Osaka Rosai Hospital, Sakai, Osaka, Japan.
J Neurosurg Spine. 2016 Nov;25(5):591-595. doi: 10.3171/2016.3.SPINE151525. Epub 2016 May 27.
OBJECTIVE Several biomechanical studies have demonstrated the favorable mechanical properties of the cortical bone trajectory (CBT) screw. However, no reports have examined surgical outcomes of posterior lumbar interbody fusion (PLIF) with CBT screw fixation for degenerative spondylolisthesis (DS) compared with those after PLIF using traditional pedicle screw (PS) fixation. The purposes of this study were thus to elucidate surgical outcomes after PLIF with CBT screw fixation for DS and to compare these results with those after PLIF using traditional PS fixation. METHODS Ninety-five consecutive patients underwent PLIF with CBT screw fixation for DS (CBT group; mean followup 35 months). A historical control group consisted of 82 consecutive patients who underwent PLIF with traditional PS fixation (PS group; mean follow-up 40 months). Clinical status was assessed using the Japanese Orthopaedic Association (JOA) scale score. Fusion status was assessed by dynamic plain radiographs and CT. The need for additional surgery and surgery-related complications was also evaluated. RESULTS The mean JOA score improved significantly from 13.7 points before surgery to 23.3 points at the latest follow-up in the CBT group (mean recovery rate 64.4%), compared with 14.4 points preoperatively to 22.7 points at final follow-up in the PS group (mean recovery rate 55.8%; p < 0.05). Solid spinal fusion was achieved in 84 patients from the CBT group (88.4%) and in 79 patients from the PS group (96.3%, p > 0.05). Symptomatic adjacent-segment disease developed in 3 patients from the CBT group (3.2%) compared with 9 patients from the PS group (11.0%, p < 0.05). CONCLUSIONS PLIF with CBT screw fixation for DS provided comparable improvement of clinical symptoms with PLIF using traditional PS fixation. However, the successful fusion rate tended to be lower in the CBT group than in the PS group, although the difference was not statistically significant between the 2 groups.
目的 多项生物力学研究已证实皮质骨轨迹(CBT)螺钉具有良好的力学性能。然而,尚无报告比较采用CBT螺钉固定的后路腰椎椎间融合术(PLIF)治疗退变性腰椎滑脱(DS)与采用传统椎弓根螺钉(PS)固定的PLIF术后的手术效果。因此,本研究的目的是阐明采用CBT螺钉固定的PLIF治疗DS后的手术效果,并将这些结果与采用传统PS固定的PLIF术后结果进行比较。方法 95例连续患者接受了采用CBT螺钉固定的PLIF治疗DS(CBT组;平均随访35个月)。一个历史对照组由82例连续接受传统PS固定的PLIF患者组成(PS组;平均随访40个月)。使用日本骨科协会(JOA)量表评分评估临床状况。通过动态X线平片和CT评估融合状况。还评估了再次手术的必要性和与手术相关的并发症。结果 CBT组患者的平均JOA评分从术前的13.7分显著提高至最近一次随访时的23.3分(平均恢复率64.4%),而PS组患者术前为14.4分,最终随访时为22.7分(平均恢复率55.8%;p<0.05)。CBT组84例患者(88.4%)实现了坚固的脊柱融合,PS组79例患者(96.3%,p>0.05)实现了坚固的脊柱融合。CBT组3例患者(3.2%)出现有症状的相邻节段疾病,而PS组9例患者(11.0%,p<0.05)出现有症状的相邻节段疾病。结论 采用CBT螺钉固定的PLIF治疗DS与采用传统PS固定的PLIF在临床症状改善方面相当。然而,CBT组的成功融合率虽低于PS组,但两组之间的差异无统计学意义。