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慢性腰腿痛患者维生素D水平的评估。

Evaluation of vitamin D levels in patients with chronic low back-leg pain.

作者信息

Çalık Yalkın, Aygün Ümit

机构信息

Abant Izzet Baysal University, İzzet Baysal Physical Medicine and Rehabilitation Training and Research Hospital, Bolu, Turkey.

Abant İzzet Baysal University, İzzet Baysal Training and Research Hospital, Department of Orthopaedics and Traumatology, Bolu, Turkey.

出版信息

Acta Orthop Traumatol Turc. 2017 May;51(3):243-247. doi: 10.1016/j.aott.2017.03.006. Epub 2017 Apr 21.

Abstract

OBJECTIVE

We aimed to examine the relationship between the levels of vitamin D and patients with chronic low back-leg pain (CLBLP) and to investigate its effects on pain and functional capacity.

METHODS

145 patients (female/male:103/42) with CLBLP, aged between 35 and 65 years (mean age: 53,06 ± 8,14), participated in the study. Visual Analog Pain Scale (VAS) was used to measure the state of pain. Pain-related functional capacity was evaluated through Oswestry Disability Index (ODI). Patients were classified into three groups based on their serum vitamin D levels: normal (≥30 ng/ml), vitamin D insufficiency (21-29 ng/ml), and vitamin D deficiency (≤20 ng/ml).

RESULTS

We found that 22,8% of patients (n:33) had vitamin D deficiency, 42,8% (n:62) had vitamin D insufficiency, and 34,5% (n:50) had normal levels of vitamin D. VAS scores were 4,75 ± 0,93; 4,66 ± 0,97 and 4,52 ± 0,90 for patients with vitamin D deficiency, vitamin D insufficiency, and normal levels of vitamin D, respectively. We found that there was no significant relationship between vitamin D level and VAS score (p>0,05). ODI scores were 18,78 ± 7,89; 15,46 ± 5,57 and 14,52 ± 7,19 for patients with vitamin D deficiency, vitamin D insufficiency, and normal levels of vitamin D, respectively. CLBLP-related functional capacity was found to be significantly lower in patients with vitamin D deficiency when compared to other two groups (p < 0,05).

CONCLUSION

Vitamin D deficiency may lead to lower functional capacity, and clinically, Vit D levels should be checked in musculoskeletal pain patients at risk of Vit D deficiency.

LEVEL OF EVIDENCE

Level IV, Diagnostic study.

摘要

目的

我们旨在研究维生素D水平与慢性腰腿疼痛(CLBLP)患者之间的关系,并探讨其对疼痛和功能能力的影响。

方法

145例年龄在35至65岁之间(平均年龄:53.06±8.14)的CLBLP患者(女性/男性:103/42)参与了本研究。采用视觉模拟疼痛量表(VAS)测量疼痛状态。通过奥斯维斯特残疾指数(ODI)评估与疼痛相关的功能能力。根据患者血清维生素D水平将其分为三组:正常(≥30 ng/ml)、维生素D不足(21 - 29 ng/ml)和维生素D缺乏(≤20 ng/ml)。

结果

我们发现22.8%的患者(n = 33)存在维生素D缺乏,42.8%(n = 62)存在维生素D不足,34.5%(n = 50)维生素D水平正常。维生素D缺乏、不足和正常的患者VAS评分分别为4.75±0.93、4.66±0.97和4.52±0.90。我们发现维生素D水平与VAS评分之间无显著关系(p>0.05)。维生素D缺乏、不足和正常的患者ODI评分分别为18.78±7.89、15.46±5.57和14.52±7.19。与其他两组相比,维生素D缺乏患者的CLBLP相关功能能力显著较低(p<0.05)。

结论

维生素D缺乏可能导致功能能力降低,临床上,对于有维生素D缺乏风险的肌肉骨骼疼痛患者应检查维生素D水平。

证据级别

IV级,诊断性研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71bf/6197560/96c85448100b/gr1.jpg

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