Cunningham Daniel J, Kavolus Joseph J, Bolognesi Michael P, Wellman Samuel S, Seyler Thorsten M
Department of Orthopaedic Surgery, Duke University School of Medicine, Durham, North Carolina.
Department of Orthopaedic Surgery, Duke University Medical Center, Durham, North Carolina.
J Arthroplasty. 2017 Sep;32(9S):S241-S245.e3. doi: 10.1016/j.arth.2017.03.037. Epub 2017 Mar 31.
Periprosthetic infection has been linked to risk factors such as diabetes, obesity, and smoking among others. This study examined the relationship between common patient comorbidities and hip periprosthetic infection outcomes.
We retrospectively reviewed the records of 149 culture-positive periprosthetic hip infections at our tertiary care center that underwent treatment between 2005 and 2015. Baseline characteristics and common comorbidities were analyzed with relation to rates of successfully treated infection, total surgeries for infection, and cumulative length of hospitalization using multivariate analysis.
Patients with coronary artery disease or anemia had significantly lower rate of successfully treated infection. Patients with anemia or chronic pulmonary disease underwent significantly more surgery, and patients with chronic pulmonary disease, psychiatric disease, anemia, or diabetes spent significantly longer time in hospital.
Potentially modifiable cardiovascular, respiratory, and psychiatric diseases were associated with a decreased rate of successfully treated infection, more surgery, and longer hospitalization in treatment for hip periprosthetic infection in multivariate analysis.
假体周围感染与糖尿病、肥胖和吸烟等风险因素有关。本研究探讨了常见患者合并症与髋关节假体周围感染结局之间的关系。
我们回顾性分析了2005年至2015年间在我们三级医疗中心接受治疗的149例培养阳性的髋关节假体周围感染病例记录。使用多变量分析，分析了基线特征和常见合并症与感染成功治疗率、感染的总手术次数以及累计住院时间之间的关系。
患有冠状动脉疾病或贫血的患者感染成功治疗率显著较低。患有贫血或慢性肺病的患者接受的手术显著更多，而患有慢性肺病、精神疾病、贫血或糖尿病的患者住院时间显著更长。
在多变量分析中，潜在可改变的心血管、呼吸和精神疾病与髋关节假体周围感染治疗中感染成功治疗率降低、手术增多和住院时间延长有关。
