Abu El-Hamd M, Farah A
Dermatology, Venereology and Andrology Department, Faculty of Medicine, Sohag University, Sohag, Egypt.
Clinical and Chemical Pathology Department, Faculty of Medicine, Sohag University, Sohag, Egypt.
Andrologia. 2018 Feb;50(1). doi: 10.1111/and.12808. Epub 2017 Apr 24.
Premature ejaculation (PE) is the most common male sexual dysfunction. This study aimed to investigate the role of serum testosterone, gonadotropins and prolactin in patients with PE. In a prospective a case-controlled study, it was conducted on 90 male patients with PE and 90 male healthy participants as controls. Patients were evaluated by Premature Ejaculation Diagnostic Tool (PEDT) and intravaginal ejaculatory latency time (IELT). Patients with mean IELT values ≤60 s and PEDT total scores ≥11 were considered to have PE. Serum levels of total testosterone (TT), free testosterone (FT), follicle-stimulating hormone (FSH), luteinising hormone (LH) and prolactin (PL) were investigated in patients with PE and controls. There was no statistically significant difference between patients with PE and controls regarding the serum levels of TT, FT, FSH, LH and PL (p value ˃.05). There was no significant correlation between the sex hormones levels (TT, FT, FSH, LH and PL) and (age, body mass index (BMI), IELTS and total PEDT scores of the patients; p value ˃.05). This study concluded that there was no disturbance in serum levels of testosterone, gonadotropins and prolactin in patients with PE and controls. These hormones could not relate to pathogenesis of PE.
早泄（PE）是最常见的男性性功能障碍。本研究旨在探讨血清睾酮、促性腺激素和催乳素在早泄患者中的作用。在一项前瞻性病例对照研究中，对90例早泄男性患者和90例健康男性参与者作为对照进行了研究。通过早泄诊断工具（PEDT）和阴道内射精潜伏期（IELT）对患者进行评估。平均IELT值≤60秒且PEDT总分≥11分的患者被认为患有早泄。对早泄患者和对照组的血清总睾酮（TT）、游离睾酮（FT）、促卵泡生成素（FSH）、黄体生成素（LH）和催乳素（PL）水平进行了研究。早泄患者和对照组在TT、FT、FSH、LH和PL的血清水平方面无统计学显著差异（p值˃.05）。性激素水平（TT、FT、FSH、LH和PL）与患者的（年龄、体重指数（BMI）、IELTS和PEDT总分）之间无显著相关性；p值˃.05）。本研究得出结论，早泄患者和对照组的血清睾酮、促性腺激素和催乳素水平无紊乱。这些激素与早泄的发病机制无关。
