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腹腔镜直肠切除术初次手术时转化和发病的危险因素:一项回顾性研究

Risk Factors for Conversion and Morbidity During Initial Experience in Laparoscopic Proctectomies: a Retrospective Study.

作者信息

Hrora Abdelmalek, Majbar Anass Mohammed, Elalaoui Mouna, Raiss Mohamed, Sabbah Farid, Ahallat Mohamed

机构信息

Clinique Chirurgicale C., Ibn Sina University Hospital, Rabat, Morocco.

Research Group in Colorectal Cancer, Faculty of Medicine, Mohamed V University, Rabat, Morocco.

出版信息

Indian J Surg. 2017 Apr;79(2):90-95. doi: 10.1007/s12262-015-1426-1. Epub 2016 Jan 11.

Abstract

The aim of this study was to determine the predictable factors for conversion during laparoscopic proctectomies, and for postoperative morbidity, in order to assist in defining the best candidates of patients for initial experience in laparoscopic proctectomies for rectal adenocarcinoma. A retrospective analysis of consecutive patients who underwent laparoscopic rectal resection for rectal adenocarcinoma operated by a single surgeon, between 2005 and 2012, were performed. Predictive factors for conversion and for postoperative morbidity were analyzed using univariate and multivariate analysis. Sixty-nine patients were included. There were 35 (50.7 %) men with a median age of 53 years. Forty-seven patients had tumors located below 8 cm from the anal verge, and sphincter-preserving surgery was performed in 52 (75.4 %) patients. Thirty-four patients were operated in the early period (before 2009). Conversion rate was 17.4 %. In multivariate analysis, the independent predictive factors for conversion were time period (before 2009) ( = 0.007, Exp. 19.9; CI (95 %) 2.2-177.4) and tumors located 8 cm above the anal verge ( = 0.028, Exp. 5.23, CI (95 %) 1.2-22.8). Twenty-two patients (31.9 %) had a complicated postoperative course. Only male gender was associated with postoperative complications ( = 0.01, CI (95 %) 1.3-11.8). Our study showed that conversion rate is influenced by surgeon's experience, and height of the tumor and that male gender is a predisposing factor for a higher morbidity rate. These results suggest that women with low rectal tumors requiring colo-anal anastomosis or abdomino-perineal resection would be the best candidates for early surgeons' experience in laparoscopic proctectomies for rectal adenocarcinoma.

摘要

本研究的目的是确定腹腔镜直肠切除术中转开腹及术后发病的可预测因素,以帮助确定直肠癌腹腔镜直肠切除术初始经验的最佳患者人选。对2005年至2012年间由单一外科医生实施腹腔镜直肠腺癌切除术的连续患者进行回顾性分析。采用单因素和多因素分析方法分析中转开腹及术后发病的预测因素。纳入69例患者。其中男性35例(50.7%),中位年龄53岁。47例患者肿瘤位于距肛缘8 cm以下,52例(75.4%)患者行保肛手术。34例患者在早期(2009年以前)接受手术。中转开腹率为17.4%。多因素分析显示,中转开腹的独立预测因素为时间段(2009年以前)(=0.007,Exp. 19.9;95%CI 2.2 - 177.4)及肿瘤位于肛缘8 cm以上(=0.028,Exp. 5.23,95%CI 1.2 - 22.8)。22例患者(31.9%)术后病程复杂。仅男性性别与术后并发症相关(=0.01,95%CI 1.3 - 11.8)。我们的研究表明,中转开腹率受外科医生经验、肿瘤高度影响,男性性别是发病率较高的易感因素。这些结果提示,对于需要行结肠肛管吻合术或腹会阴联合切除术的低位直肠肿瘤女性患者,是早期外科医生进行腹腔镜直肠癌切除术经验积累的最佳人选。

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