Agha A, Fürst A, Iesalnieks I, Fichtner-Feigl S, Ghali N, Krenz D, Anthuber M, Jauch K W, Piso P, Schlitt H J
Klinik und Poliklinik für Chirurgie, Universität Regensburg, Franz-Josef-Strauss-Allee 11, 93053 Regensburg, Germany.
Int J Colorectal Dis. 2008 Apr;23(4):409-17. doi: 10.1007/s00384-007-0425-5.
The negative influence of conversion from laparoscopic to open colorectal resection on early postoperative morbidity and outcome has been demonstrated several times. In this study, we analyzed the conversion rate and its influence on early postoperative morbidity and short-term oncological outcome following laparoscopic rectal resections.
From January 1998 to December 2006, 300 patients underwent laparoscopic resection due to rectal carcinoma at our institution. We compared the converted patient group with the non-converted patient group regarding demographical, clinical, surgical, and histological data, compounded with the early and late postoperative results.
Two hundred seventy-four (91.3%) patients underwent laparoscopic rectal resection (LR), while conversion resection (CR) was necessary in 26 cases (8.6%). Conversion rate was 13% during the first 100 resections and decreased to 3% during the last 100 procedures (p = 0.035). Male gender, higher body mass index, and presence of T4-tumor were risk factors for conversion. Early postoperative complications were more frequent in the CR group than in the LR group. Concerning local tumor recurrence and overall survival, there was no significant difference between both groups (local recurrence, CR at 3.8% vs. LR at 4.5% and overall survival rate, CR at 76.9% vs. LR at 89.1%) after a median follow-up period of 22.5 months.
Conversion to an open procedure during laparoscopic rectal resection correlates with an increased postoperative morbidity, however, without impairment of the short-term oncological outcome. The conversion rate is minimized by the growing experience of the operating surgeon and, therefore, is a marker of the learning curve.
腹腔镜结直肠癌切除术转为开腹手术对术后早期发病率和预后的负面影响已多次得到证实。在本研究中,我们分析了腹腔镜直肠癌切除术后的中转率及其对术后早期发病率和短期肿瘤学预后的影响。
1998年1月至2006年12月,我院300例患者因直肠癌接受了腹腔镜切除术。我们比较了中转组和未中转组的人口统计学、临床、手术和组织学数据,以及术后早期和晚期结果。
274例(91.3%)患者接受了腹腔镜直肠癌切除术(LR),26例(8.6%)需要中转开腹手术(CR)。前100例手术的中转率为13%,最后100例手术的中转率降至3%(p = 0.035)。男性、较高的体重指数和T4期肿瘤是中转的危险因素。CR组术后早期并发症比LR组更常见。在中位随访22.5个月后,两组在局部肿瘤复发和总生存率方面无显著差异(局部复发,CR组为3.8%,LR组为4.5%;总生存率,CR组为76.9%,LR组为89.1%)。
腹腔镜直肠癌切除术中转为开腹手术与术后发病率增加相关,但不影响短期肿瘤学预后。随着手术医生经验的增加,中转率降至最低,因此,中转率是学习曲线的一个标志。