Burud Ismail A S, How Ng Sze, CheeWei Gan, Roslina Suboh
Department of Surgery, Clinical School, International Medical University, Seremban, 70300 Malaysia.
NSCMH Medical Centre, Jalan Tun Dr Ismail, Seremban, 70200 Malaysia.
Indian J Surg. 2017 Apr;79(2):169-172. doi: 10.1007/s12262-016-1502-1. Epub 2016 May 16.
Dermatofibrosarcoma protuberans (DFSP) is an uncommon slow growing neoplasm of the dermis with tendency to invade the subcutaneous tissues. It presents during the third to fourth decade of life and is commonly seen over the trunk, extremities and head and neck. DFSP presenting as a breast lump is rare but few cases have been reported in the literature. Pre-operative diagnosis with mammography, ultrasonography and FNAC is challenging. We report a case of a DFSP of the right breast in a middle aged lady with history of recurrent breast lumps excised and diagnosed in the past as benign. She presented with progressively increasing right breast lump of 2 months duration. She underwent wide local excision and histology revealed dermatofibrosarcoma protuberans. In view of its local aggressiveness with incomplete surgical margin, mastectomy was performed.
隆突性皮肤纤维肉瘤(DFSP)是一种罕见的、生长缓慢的真皮肿瘤,有侵犯皮下组织的倾向。它多在30至40岁出现,常见于躯干、四肢以及头颈部。以乳腺肿块形式出现的DFSP很罕见,但文献中已有少数病例报道。通过乳房X线摄影、超声检查和细针穿刺抽吸活检进行术前诊断具有挑战性。我们报告一例中年女性右乳DFSP病例,该患者既往有反复切除乳腺肿块的病史,过去诊断为良性。她出现了持续2个月的右乳肿块且逐渐增大。她接受了广泛局部切除,组织学检查显示为隆突性皮肤纤维肉瘤。鉴于其局部侵袭性且手术切缘不完整,遂行乳房切除术。