Jung Sunyoung, Hwang Bo-Mi, Jung HyunJu, Chung GyungTae, Yoo Cheon-Kwon, Lee Deog-Yong
Division of Enteric Diseases, Center for Infectious Diseases, National Research Institute of Health, Osong, Korea.
Osong Public Health Res Perspect. 2017 Feb;8(1):86-90. doi: 10.24171/j.phrp.2017.8.1.12. Epub 2017 Feb 28.
Human norovirus are major causative agent of nonbacterial acute gastroenteritis. In general, genogroup (G) II.4 is the most prominent major genotype that circulate in human population and the environment. However, a shift in genotypic trends was observed in Korea in December 2014. In this study, we investigated the trend of norovirus genotype in detail using the database of Acute Diarrhea Laboratory Surveillance (K-EnterNet) in Korea. GII.17 has since become a major contributor to outbreaks of norovirus-related infections and sporadic cases in Korea, although the reason for this shift remain unknown.
人诺如病毒是非细菌性急性胃肠炎的主要病原体。一般来说,基因群(G)II.4是在人群和环境中传播的最主要的主要基因型。然而,2014年12月在韩国观察到基因型趋势发生了变化。在本研究中,我们利用韩国急性腹泻实验室监测(K-EnterNet)数据库详细调查了诺如病毒基因型的趋势。此后,GII.17已成为韩国诺如病毒相关感染暴发和散发病例的主要原因,尽管这种变化的原因尚不清楚。