Sánchez Pérez M, Jiménez Marrero P, Kim Lee D, Neumann M P, Jorge Pérez N, Hernández Hernández C, Hernández Escobar S, Marrero Domínguez R
Servicio de Urología HUGCDN Barranco de la Ballena s/n Las Palmas de Gran Canaria, Spain.
Urol Case Rep. 2017 Apr 19;13:48-50. doi: 10.1016/j.eucr.2017.03.027. eCollection 2017 Jul.
We hereby present the case of a 55 years old patient with clinical diagnosis of high-risk prostate cancer T2bN1Mo Gleason 9 (4 + 5) treated with androgen deprivation therapy and external beam radiotherapy. Despite treatment, castration levels were not achieved and clinical progression was evidenced by the appearance of bone metastases and progression of PSA. After several hormonal treatments without any PSA or testosterone response, surgical castration was performed by bilateral orchiectomy. The pathology results showed an incidental Leydig cell tumor in the right testicle.
我们在此呈现一例55岁患者的病例，其临床诊断为高危前列腺癌T2bN1Mo， Gleason评分9（4 + 5），接受了雄激素剥夺疗法和外照射放疗。尽管进行了治疗，但仍未达到去势水平，且出现骨转移和前列腺特异性抗原（PSA）进展，证明了临床进展。在经过几次激素治疗且PSA或睾酮均无反应后，通过双侧睾丸切除术进行了手术去势。病理结果显示右侧睾丸存在偶然发现的Leydig细胞瘤。
