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响尾蛇咬伤导致的深静脉血栓形成相关的筋膜间室综合征:一例报告。

The Compartment Syndrome Associated with Deep Vein Thrombosis due to Rattlesnake Bite: A Case Report.

机构信息

Toxicology-Intensive Care Unit, Bucharest Clinical Emergency Hospital, Bucharest, Romania.

Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.

出版信息

Balkan Med J. 2017 Aug 4;34(4):367-370. doi: 10.4274/balkanmedj.2016.0218. Epub 2017 Apr 13.

DOI:10.4274/balkanmedj.2016.0218
PMID:28443568
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5617890/
Abstract

BACKGROUND

Snakebite is a health issue specific to some parts of the world, especially in the tropical areas, where it produces many victims. The main clinical damage caused by snakebite involves haemotoxic, neurotoxic and myotoxic reactions. We report the case of a young woman suffering from snakebite who developed deep vein thrombosis and compartment syndrome.

CASE REPORT

We present the case of a 32-year-old Romanian woman who was injured by her own Crotalinae snake (also known as pit viper or rattlesnake) on her left forearm. When admitted to our Emergency Department, she was conscious with a Glasgow coma scale of 12/15, somnolent, febrile, suffering of headache, tachypnoea; the marks of the snakebite were located in the distal part of the anterior left forearm; she had pain and bleeding at the bite site and swelling of the left upper limb with lymphangitis up to the axilla. She experienced fasciotomy-requiring compartment syndrome of the upper limb and required unfractionated heparin and close monitoring using activated partial thromboplastin time evolution due to micro-thrombosis in the brachial vein. Local improvement was achieved in the next 4 days with progressive diminishment of local tenderness and swelling.

CONCLUSION

Limb deep vein thrombosis might be induced by snakebite, despite the pro-haemorrhagic general condition induced by the envenomation. A high index of clinical suspicion is needed for early diagnosis and timely management, which can improve survival of these patients.

摘要

背景

蛇伤是世界上某些地区特有的健康问题,尤其是在热带地区,那里有很多受害者。蛇伤引起的主要临床损伤涉及血液毒性、神经毒性和肌毒性反应。我们报告了一例因蛇伤导致深静脉血栓形成和筋膜间室综合征的年轻女性病例。

病例报告

我们报告了一例 32 岁罗马尼亚女性,她的左前臂被自己的响尾蛇(也称为蝮蛇或响尾蛇)咬伤。当她被送入我们的急诊部时,她意识清醒,格拉斯哥昏迷评分 12/15,嗜睡,发热,头痛,呼吸急促;蛇伤的痕迹位于左前臂前远端;咬伤部位疼痛、出血,左上肢肿胀,淋巴管炎延伸至腋窝。她出现需要行筋膜切开术的上肢筋膜间室综合征,并因肱静脉微血栓形成需要使用未分馏肝素和密切监测激活部分凝血活酶时间的演变。在接下来的 4 天内,局部情况得到改善,局部压痛和肿胀逐渐减轻。

结论

尽管蛇伤引起的全身出血倾向,但肢体深静脉血栓形成可能由蛇伤引起。需要高度的临床怀疑指数进行早期诊断和及时治疗,这可以提高这些患者的生存率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fae9/5617890/0b4a9fcedf12/BMJ-34-367-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fae9/5617890/d3f16b8e976a/BMJ-34-367-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fae9/5617890/6295677b3eb5/BMJ-34-367-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fae9/5617890/0b4a9fcedf12/BMJ-34-367-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fae9/5617890/d3f16b8e976a/BMJ-34-367-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fae9/5617890/6295677b3eb5/BMJ-34-367-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fae9/5617890/0b4a9fcedf12/BMJ-34-367-g3.jpg

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