Ross Jonathan, Felsen Uriel R, Cunningham Chinazo O, Patel Viraj V, Hanna David B
1 Division of General Internal Medicine, Department of Medicine, Montefiore Medical Center , Bronx, New York.
2 Division of Infectious Diseases, Department of Medicine, Montefiore Medical Center , Bronx, New York.
AIDS Res Hum Retroviruses. 2017 Oct;33(10):1038-1044. doi: 10.1089/AID.2017.0015. Epub 2017 May 22.
HIV-infected undocumented immigrants face unique barriers to care yet little is known about their clinical outcomes. We performed a retrospective cohort study of HIV-infected adults in clinical care from 2006 to 2014 at a large academic medical center in a setting where medical insurance is available to HIV-infected undocumented immigrants. Undocumented status was assessed based on Social Security number and insurance status and verified through medical chart review. Using Poisson regression models, we compared undocumented and documented patients with respect to retention in care (≥2 HIV-related laboratory tests ≥90 days apart), antiretroviral therapy (ART) prescription (≥3 active antiretroviral agents prescribed in a year), and viral suppression (HIV RNA <200 copies/ml for the last measured viral load) for each year in care. Of 7,551 patients included in the analysis, we classified 173 (2.3%) as undocumented. For each year of the analysis, higher proportions of undocumented patients were retained in care, prescribed ART, and virally suppressed. In adjusted models, undocumented status was associated with increased probability of retention in care [risk ratio (RR) 1.05, confidence interval (95% CI) 1.01-1.09], ART prescription (RR 1.05, 95% CI 1.01-1.08), and viral suppression (RR 1.13, 95% CI 1.08-1.19) compared to documented status. Undocumented patients achieved clinical outcomes at modestly higher rates than documented patients, despite entering care with more advanced disease. In a setting where insurance is available to undocumented patients, similar outcomes along the HIV care continuum may be achieved regardless of immigration status.
感染艾滋病毒的无证移民在获得医疗护理方面面临独特障碍,但对于他们的临床结局却知之甚少。我们在一家大型学术医疗中心进行了一项回顾性队列研究,研究对象为2006年至2014年接受临床护理的感染艾滋病毒的成年人,该中心所在地区为感染艾滋病毒的无证移民提供医疗保险。根据社会保险号码和保险状况评估无证状态,并通过病历审查进行核实。我们使用泊松回归模型,比较了无证患者和有证患者在接受护理期间(间隔≥90天进行≥2次与艾滋病毒相关的实验室检测)、抗逆转录病毒疗法(ART)处方(一年内开具≥3种活性抗逆转录病毒药物)以及每年病毒抑制(最后一次检测的病毒载量时艾滋病毒RNA<200拷贝/毫升)方面的情况。在纳入分析的7551名患者中,我们将173名(2.3%)归类为无证患者。在分析的每一年中,无证患者接受护理、开具ART处方以及实现病毒抑制的比例更高。在调整后的模型中,与有证状态相比,无证状态与接受护理的可能性增加相关[风险比(RR)1.05,置信区间(95%CI)1.01 - 1.09]、ART处方(RR 1.05,95%CI 1.01 - 1.08)以及病毒抑制(RR 1.13,95%CI 1.08 - 1.19)。尽管无证患者开始接受护理时疾病更为严重,但他们实现临床结局的比率略高于有证患者。在为无证患者提供保险的环境中,无论移民身份如何,在艾滋病毒护理连续过程中可能会取得类似的结局。