Stoner Rebecca, Camilleri Victoria, Calleja-Agius Jean, Schembri-Wismayer Pierre
a Department of Anatomy , Faculty of Medicine and Surgery, University of Malta , Msida , Malta.
Gynecol Endocrinol. 2017 Aug;33(8):588-592. doi: 10.1080/09513590.2017.1318367. Epub 2017 Apr 26.
Premenstrual syndrome (PMS) and related disorders, and postpartum depression (PPD) can affect women to the extent that their quality of life and that of their near ones can be severely impaired. This review focuses on the different theories regarding the etiologies of PMS and PPD, and attempts to draw a link between the two. Theories focus mainly on hormonal and cytokine factors throughout different phases in the female reproductive cycle. Changes in this symptomatology during pregnancy are also reviewed, as are changes in hormones and cytokine levels. Hypotheses are thus developed as to why the symptoms experienced in PMS often subside during pregnancy yet may recur and be exacerbated after birth, giving rise to the symptoms experienced in PPD.
经前综合征（PMS）及相关疾病，以及产后抑郁症（PPD）对女性的影响极大，会严重损害她们及其亲人的生活质量。本综述聚焦于关于PMS和PPD病因的不同理论，并试图在两者之间建立联系。这些理论主要关注女性生殖周期不同阶段的激素和细胞因子因素。还综述了孕期这种症状学的变化，以及激素和细胞因子水平的变化。由此提出了一些假设，解释为何PMS所经历的症状在孕期往往会缓解，但在产后可能复发并加重，从而引发PPD所经历的症状。
