Baker Brian J, Peterson Brandy, Mohanlall Jeetendra, Singh Shanti, Hicks Collene, Jacobs Ruth, Ramos Ruth, Allen Barbara, Pevzner Eric
U.S. Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.
Ministry of Health, National TB Programme, Georgetown, Guyana.
Rev Panam Salud Publica. 2017 Apr 20;41:e6. doi: 10.26633/RPSP.2017.6.
To assess scale-up of recommended tuberculosis (TB)/HIV activities in Guyana and to identify specific strategies for further expansion.
Medical records and clinic registers were reviewed at nine TB clinics and 10 HIV clinics. At TB clinics, data were collected on HIV testing and antiretroviral therapy (ART) for patients with TB/HIV; at HIV clinics, data were collected on intensified case finding (ICF), tuberculin skin test (TST) results, and provision of isoniazid preventive therapy (IPT).
At TB clinics, among 461 patients newly diagnosed with TB, 419 (90.9%) had a known HIV status and 121 (28.9%) were HIV-infected. Among the 63 patients with TB/HIV, 33 (52.4%) received ART. Among the 45 patients with TB/HIV for whom dates of HIV diagnosis were available, 38 (84.4%) individuals knew their HIV status prior to TB diagnosis. At HIV clinics, among 127 patients eligible to receive a TST, 87 (68.5%) received a TST, 66 (75.9%) had a TST result, seven (10.6%) had a newly positive result, two had a previously positive result, and six of nine patients with positive results (66.7%) received IPT. ICF could not be assessed because of incomplete or discrepant documentation.
An in-depth evaluation of TB/HIV activities successfully identified areas of success and remaining challenges. At TB clinics, HIV testing rates are high; further scale-up of ART for persons with TB/HIV is needed. At HIV clinics, use of TST to focus IPT is a feasible and efficient strategy; improving rates of annual TST screening will allow for further expansion of IPT.
评估圭亚那推荐的结核病(TB)/艾滋病病毒(HIV)活动的扩大规模情况,并确定进一步扩大的具体策略。
对9家结核病诊所和10家HIV诊所的病历和诊所登记册进行了审查。在结核病诊所,收集了结核病/HIV患者的HIV检测和抗逆转录病毒治疗(ART)数据;在HIV诊所,收集了强化病例发现(ICF)、结核菌素皮肤试验(TST)结果以及异烟肼预防性治疗(IPT)的提供情况数据。
在结核病诊所,461例新诊断为结核病的患者中,419例(90.9%)已知HIV感染状况,121例(28.9%)感染了HIV。在63例结核病/HIV患者中,33例(52.4%)接受了ART。在45例有HIV诊断日期的结核病/HIV患者中,38例(84.4%)在结核病诊断之前就知道自己的HIV感染状况。在HIV诊所,127例 eligible to receive a TST的患者中,87例(68.5%)接受了TST,66例(75.9%)有TST结果,7例(10.6%)有新的阳性结果,2例有既往阳性结果,9例阳性结果患者中的6例(66.7%)接受了IPT。由于文件不完整或不一致,无法评估ICF。
对结核病/HIV活动的深入评估成功确定了成功领域和剩余挑战。在结核病诊所,HIV检测率很高;需要进一步扩大对结核病/HIV患者的ART治疗。在HIV诊所,使用TST来集中IPT是一种可行且有效的策略;提高年度TST筛查率将有助于进一步扩大IPT。