儿童麻风病
Leprosy in Children.
作者信息
Barreto Josafá Gonçalves, Frade Marco Andrey Cipriani, Bernardes Filho Fred, da Silva Moises Batista, Spencer John Stewart, Salgado Claudio Guedes
机构信息
Spatial Epidemiology Laboratory, Federal University of Pará, Campus Castanhal, Avenida dos Universitários, s/n, Bairro Jaderlândia Castanhal, Pará, CEP: 68746-360, Brazil.
Divison of Dermatology of Internal Medicine, Department of Ribeirão Preto Medical School, University of São Paulo, Av. Bandeirantes, 3900, Monte Alegre, Ribeirão Preto, São Paulo, CEP: 14.049.900, Brazil.
出版信息
Curr Infect Dis Rep. 2017 Jun;19(6):23. doi: 10.1007/s11908-017-0577-6.
PURPOSE OF REVIEW
This manuscript aims to review the cutting-edge developments regarding to the diagnosis, management, and prevention of leprosy in children.
RECENT FINDINGS
Leprosy transmission still occurs continuously in some endemic areas in the world. Leprosy in children below 15 years old is a robust indicator of active source of infection in the community where they live. A special focus on children to reduce disabilities and reduce transmission is one of the core areas of interventions of the global leprosy strategy 2016-2020. Ongoing research is trying to develop better diagnostic tests and to advance chemoprophylaxis and immunoprophylaxis approaches. Early diagnosis in children can be hard because of the wide range of clinical aspects of the skin lesions and mainly due to the difficulty of performing the clinical peripheral nerve evaluation. We must maintain leprosy expertise and improve the health professionals training for leprosy diagnosis, since we still have a long journey to reach leprosy elimination.
综述目的
本手稿旨在回顾儿童麻风病诊断、管理和预防方面的前沿进展。
最新发现
在世界上一些流行地区，麻风病仍在持续传播。15岁以下儿童患麻风病是其所在社区存在活跃传染源的有力指标。特别关注儿童以减少残疾和减少传播是2016 - 2020年全球麻风病战略干预的核心领域之一。正在进行的研究试图开发更好的诊断测试，并推进化学预防和免疫预防方法。由于皮肤病变的临床症状范围广泛，主要是由于进行临床周围神经评估存在困难，儿童早期诊断可能会很困难。我们必须保持麻风病专业知识，并改善卫生专业人员的麻风病诊断培训，因为要实现消除麻风病的目标，我们仍有很长的路要走。
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