一例大脑中动脉闭塞自发再通后发生脑过度灌注的病例：再灌注损伤还是真正的脑过度灌注综合征？
A case of cerebral hyperperfusion following spontaneous recanalization of occluded middle cerebral artery: Reperfusion injury or true cerebral hyperperfusion syndrome?
作者信息
Xu Ziqi, Zhou Jiajia, Liang Hui, Luo Benyan, Liu Ping
机构信息
Department of Neurology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
出版信息
Medicine (Baltimore). 2017 Apr;96(17):e6740. doi: 10.1097/MD.0000000000006740.
BACKGROUND
Cerebral hyperperfusion syndrome (CHS) and reperfusion injury are distinct pathological phenomena.
CASE SUMMARY
We present the case of a young ischemic stroke patient with middle cerebral artery (MCA) occlusion and spontaneous recanalization. Follow-up transcranial Doppler ultrasound showed high velocity flow in the left MCA, and neuroimaging revealed infarction, brain edema, artery dilatation, and hyperperfusion, consistent with both CHS and reperfusion injury.
CONCLUSION
In cases with signs of both CHS and reperfusion injury, we speculate that CHS may be both a contributor to and a manifestation of reperfusion injury.
背景
脑过度灌注综合征（CHS）和再灌注损伤是不同的病理现象。
病例摘要
我们报告一例年轻的缺血性脑卒中患者，其大脑中动脉（MCA）闭塞并自发再通。随访经颅多普勒超声显示左侧MCA血流速度高，神经影像学检查发现梗死、脑水肿、动脉扩张和过度灌注，符合CHS和再灌注损伤。
结论
在同时出现CHS和再灌注损伤迹象的病例中，我们推测CHS可能既是再灌注损伤的促成因素，也是其表现形式。
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