Pezzilli Raffaele, Pagano Nico
Department of Digestive Diseases Sant'Orsola-Malpighi Hospital Bologna, Bologna, Italy.
Dig Dis. 2017;35(5):449-453. doi: 10.1159/000471481. Epub 2017 Apr 27.
Data regarding the involvement of the pancreas during the course of inflammatory bowel disease (IBD) are scarce and conflicting.
To assess the frequency of benign pancreatic diseases, that is, acute pancreatitis, chronic pancreatitis (CP), and autoimmune pancreatitis (AIP), in a population with IBD.
A search for patients with IBD who presented at our hospital between January 2006 and January 2015 with a diagnosis of IBD was carried out.
A total of 5,242 patients with IBD were included in this study (2,838 males, 54.1%, and 2,404 females, 45.9%, mean age 43.7 years, range 18-101 years). Of these 5,242 patients, 3,201 (61.1%) had Crohn's disease and 2,041 (38.9%) had ulcerative colitis (UC).
Thirteen patients developed benign pancreatic diseases (0.2%). Eight patients had acute pancreatitis (0.2%; 4 in the Crohn's disease group and 4 in the UC group), 3 had CP (0.1%, 2 in the Crohn's disease group and 1 in the UC group), 2 had AIP (0.04%), all in the group of diffuse UC (p = 0.321).
The frequency of benign pancreatic disease was not high in patients with IBD and was probably similar to that seen in the general population.
关于炎症性肠病（IBD）病程中胰腺受累的数据稀少且相互矛盾。
评估IBD患者群体中良性胰腺疾病，即急性胰腺炎、慢性胰腺炎（CP）和自身免疫性胰腺炎（AIP）的发生率。
对2006年1月至2015年1月期间在我院就诊并诊断为IBD的患者进行检索。
本研究共纳入5242例IBD患者（男性2838例，占54.1%；女性2404例，占45.9%；平均年龄43.7岁，范围18 - 101岁）。在这5242例患者中，3201例（61.1%）患有克罗恩病，2041例（38.9%）患有溃疡性结肠炎（UC）。
13例患者发生良性胰腺疾病（0.2%）。8例患有急性胰腺炎（0.2%；克罗恩病组4例，UC组4例），3例患有CP（0.1%，克罗恩病组2例，UC组1例），2例患有AIP（0.04%），均在弥漫性UC组（p = 0.321）。
IBD患者中良性胰腺疾病的发生率不高，可能与普通人群相似。
