哮喘的热消融治疗：现状与技术
Thermal ablation for asthma: current status and technique.
作者信息
Krmisky William, Sobieszczyk Michal J, Sarkar Saiyad
机构信息
Interventional Pulmonary and Critical Care Medicine, MedStar Franklin Square Hospital Center, Baltimore, Maryland, USA.
Pulmonary and Critical Care Medicine, Walter Reed National Military Medical Center, Bethesda, Maryland, USA.
出版信息
J Thorac Dis. 2017 Mar;9(Suppl 2):S104-S109. doi: 10.21037/jtd.2016.11.113.
Bronchial thermoplasty (BT) is a novel technique used in the treatment of severe asthma. A catheter is advanced through the bronchoscope and directed radiofrequency waves are applied to the segmental bronchi to reduce airway smooth muscle mass. Several randomized clinical trials demonstrate improvement in quality of life and reduction in exacerbation rates after treatment. BT is a safe and cost effective treatment option for severe asthma which is refractory to medical treatment. Further studies are needed in order to better describe the mechanism of action and the asthma subphenotype that was best benefit from this treatment.
支气管热成形术（BT）是一种用于治疗重度哮喘的新技术。通过支气管镜插入一根导管，并将定向射频波应用于段支气管，以减少气道平滑肌质量。多项随机临床试验表明，治疗后生活质量得到改善，病情加重率降低。BT是一种安全且具有成本效益的治疗选择，适用于药物治疗无效的重度哮喘。需要进一步研究以更好地描述其作用机制以及最能从该治疗中获益的哮喘亚表型。
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