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[神经性皮炎:皮肤的特应性]

[Neurodermatitis : Atopy of the skin].

作者信息

Fölster-Holst R

机构信息

Klinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Rosalind-Franklin-Str. 7, 24105, Kiel, Deutschland.

出版信息

Ophthalmologe. 2017 Jun;114(6):498-503. doi: 10.1007/s00347-017-0495-x.

DOI:10.1007/s00347-017-0495-x
PMID:28447153
Abstract

Atopic dermatitis is one of the most common skin diseases and is associated with an impaired quality of life due to tormenting itching and stigmatization. The disease almost always manifests in early childhood and exhibits specific features in this phase, with involvement of the extensor sides of the extremities. During the further course of disease, the typical flexor involvement becomes quite clear and a considerable proportion of patients develop the associated atopic respiratory diseases. Therapeutic and prophylactic measures focus on the prevention of trigger factors, basic skin care, and application of lipid-replenishing creams, as well as patient and parent education. In the case of exacerbation, anti-inflammatory drugs are treatment of choice.

摘要

特应性皮炎是最常见的皮肤病之一,由于剧烈瘙痒和污名化,它会导致生活质量下降。这种疾病几乎总是在幼儿期出现,并在这个阶段表现出特定特征,累及四肢伸侧。在疾病的进一步发展过程中,典型的屈侧受累变得很明显,相当一部分患者会患上相关的特应性呼吸道疾病。治疗和预防措施侧重于预防触发因素、基础皮肤护理、涂抹补充脂质的乳膏,以及对患者和家长的教育。在病情加重的情况下,抗炎药物是首选治疗方法。

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本文引用的文献

1
[Epidermal barrier disorders in dermatoses].[皮肤病中的表皮屏障障碍]
Hautarzt. 2016 Nov;67(11):907-921. doi: 10.1007/s00105-016-3883-2.
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Anti-inflammatory therapies in atopic dermatitis.特应性皮炎的抗炎治疗。
Allergy. 2016 Dec;71(12):1666-1675. doi: 10.1111/all.13065.
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Characteristics of peripheral blood CD4+CD25+ regulatory T cells and related cytokines in severe atopic dermatitis.重度特应性皮炎患者外周血CD4+CD25+调节性T细胞及相关细胞因子的特征
Eur J Dermatol. 2016 Jun 1;26(3):240-6. doi: 10.1684/ejd.2015.2709.
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ETFAD/EADV Eczema task force 2015 position paper on diagnosis and treatment of atopic dermatitis in adult and paediatric patients.欧洲皮肤病与性病学会/欧洲变态反应与临床免疫学会湿疹工作组2015年关于成人及儿童特应性皮炎诊断与治疗的立场文件。
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S2k guideline on diagnosis and treatment of atopic dermatitis--short version.特应性皮炎诊疗指南S2k——简版
J Dtsch Dermatol Ges. 2016 Jan;14(1):92-106. doi: 10.1111/ddg.12871.
7
Birch pollen influence the severity of atopic eczema - prospective clinical cohort pilot study and ex vivo penetration study.桦树花粉影响特应性皮炎的严重程度——前瞻性临床队列试点研究和体外渗透研究。
Clin Cosmet Investig Dermatol. 2015 Oct 29;8:539-48. doi: 10.2147/CCID.S81700. eCollection 2015.
8
Autoallergy in atopic dermatitis.特应性皮炎中的自身过敏反应。
Allergo J Int. 2015;24(1):16-22. doi: 10.1007/s40629-015-0037-5. Epub 2015 Feb 9.
9
S3-Guideline on allergy prevention: 2014 update: Guideline of the German Society for Allergology and Clinical Immunology (DGAKI) and the German Society for Pediatric and Adolescent Medicine (DGKJ).《过敏预防S3指南:2014年更新版》:德国变态反应与临床免疫学会(DGAKI)及德国儿科与青少年医学学会(DGKJ)指南
Allergo J Int. 2014;23(6):186-199. doi: 10.1007/s40629-014-0022-4.
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Exacerbation of atopic dermatitis on grass pollen exposure in an environmental challenge chamber.在环境挑战舱中因接触草花粉而使特应性皮炎恶化。
J Allergy Clin Immunol. 2015 Jul;136(1):96-103.e9. doi: 10.1016/j.jaci.2015.04.015. Epub 2015 Jun 1.