Park So Young, Kim Sun Young, Lee Hye Mi, Hur Kyu Yeon, Kim Jae Hyeon, Lee Moon Kyu, Sim Kang Hee, Jin Sang Man
Division of Endocrinology and Metabolism, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Diabetes Education Unit, Diabetes Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Diabetes Metab J. 2017 Apr;41(2):99-112. doi: 10.4093/dmj.2017.41.2.99.
Despite the established benefits of diabetes camps for the continuing education of children with type 1 diabetes mellitus, little is known about the long-term metabolic benefits of diabetes camps for middle-aged and elderly people with type 2 diabetes mellitus (T2DM), especially in terms of glycosylated hemoglobin (HbA1c) variability.
The 1-year mean and variability of HbA1c before and after the diabetes camp was compared between the participants of the diabetes camp (n=57; median age 65 years [range, 50 to 86 years]; median diabetes duration 14 years [range, 1 to 48 years]). Additional case-control analysis compared the metabolic outcomes of the participants of the diabetes camp and their propensity score-matched controls who underwent conventional diabetes education (n=93).
The levels of HbA1c during the first year after the diabetes camp were comparable to those of the matched controls (P=0.341). In an analysis of all participants of the diabetes camp, the 1-year mean±standard deviation (SD) of HbA1c decreased (P=0.010 and P=0.041) after the diabetes camp, whereas the adjusted SD and coefficient of variance (CV) of HbA1c did not decrease. The adjusted SD and CV significantly decreased after the diabetes camp in participants whose 1-year mean HbA1c was ≥6.5% before the diabetes camp (n=40) and those with a duration of diabetes less than 15 years (n=32).
The 1-year mean and SD of HbA1c decreased after the diabetes camp, with significant reduction in the adjusted SD and CV in those with higher baseline HbA1c and a shorter duration of diabetes.
尽管糖尿病营对1型糖尿病儿童的继续教育有既定益处,但对于2型糖尿病(T2DM)中老年患者而言,糖尿病营的长期代谢益处知之甚少,尤其是在糖化血红蛋白(HbA1c)变异性方面。
比较了糖尿病营参与者(n = 57;年龄中位数65岁[范围50至86岁];糖尿病病程中位数14年[范围1至48年])在参加糖尿病营前后HbA1c的1年平均值和变异性。额外的病例对照分析比较了糖尿病营参与者及其倾向评分匹配的接受传统糖尿病教育的对照者(n = 93)的代谢结果。
糖尿病营后第一年的HbA1c水平与匹配对照者相当(P = 0.341)。在对糖尿病营所有参与者的分析中,糖尿病营后HbA1c的1年平均值±标准差(SD)降低(P = 0.010和P = 0.041),而HbA1c的调整后SD和变异系数(CV)未降低。在糖尿病营前1年平均HbA1c≥6.5%的参与者(n = 40)和糖尿病病程小于15年的参与者(n = 32)中,糖尿病营后调整后SD和CV显著降低。
糖尿病营后HbA1c的1年平均值和SD降低,基线HbA1c较高且糖尿病病程较短者的调整后SD和CV显著降低。