Guldogan Cem Emir, Çetinkaya Erdinç, Akgul Ozgur, Tez Mesut
Ann Ital Chir. 2017;88:43-47.
Malnutrition is a common and very important issue in colorectal cancer patients.The immunological and nutritional status of these patients have been reported to be correlated with the postoperative complications.The prognostic nutritional index (PNI) is an effective and simple parameter, initially created to evaluate preoperative surgical risks. The aim of this study was to evaluate the predictive value of PNI in patients with colorectal cancer who underwent surgery.
One hundred eighty patients who underwent curative colorectal resections for colorectal cancer were included in this retrospective study. Demographic characteristics of the patients, biochemical parameters, intra-operative findings, operation type, postoperative surgical complications, and PNI values were collected Results:The median PNI value was 44,4(range 19-60,5).Receiver Operating Characteristics demonstrated that a value below 39,75 was the optimal cut-off value for the prediction of major complications. The median PNI values were significantly lower in patients with major complications (Clavien-Dindo grade 3 to 5).
The PNI can predict severe complications in patients with colorectal cancer who are undergoing primary tumor resection. Investigation of the nutritional status by using the PNI could be a useful approach for clinical follow-up.
Colorectal, Nutritional index, Postoperative complications.
营养不良是结直肠癌患者中常见且非常重要的问题。据报道，这些患者的免疫和营养状况与术后并发症相关。预后营养指数（PNI）是一个有效且简单的参数，最初用于评估术前手术风险。本研究的目的是评估PNI在接受手术的结直肠癌患者中的预测价值。
本回顾性研究纳入了180例行结直肠癌根治性切除术的患者。收集患者的人口统计学特征、生化参数、术中发现、手术类型、术后手术并发症及PNI值。结果：PNI值中位数为44.4（范围19 - 60.5）。受试者工作特征曲线显示，低于39.75是预测主要并发症的最佳临界值。主要并发症（Clavien-Dindo 3至5级）患者的PNI值中位数显著更低。
PNI可预测接受原发性肿瘤切除的结直肠癌患者的严重并发症。通过PNI评估营养状况可能是临床随访的一种有用方法。
结直肠癌；营养指数；术后并发症
