Yang Jenny, Martinez Maria, Schwartz Todd A, Beeber Linda
1 Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina.
2 School of Nursing, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina.
J Womens Health (Larchmt). 2017 Jun;26(6):683-691. doi: 10.1089/jwh.2016.5974. Epub 2017 Apr 27.
Adequate assessment of depressive symptomatology is a necessary step toward decreasing income-related mental health treatment inequity. No studies have focused on comparing instruments used to detect depression in women from low-income backgrounds who are mothers of young children-a period of increased risk for depressive symptoms.
To address this gap, two commonly used instruments (Center for Epidemiologic Studies Depression Scale [CES-D] and Hamilton Rating Scale for Depression [Hamilton]) were compared with a depression diagnosis (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition [DSM-V]) in a sample (n = 251) of mothers from low-income backgrounds with children ranging from 1 to 54 months old. Diagnostic utility was examined in light of contextual factors associated with maternal depressive symptoms.
In this sample, CES-D had better screening sensitivity and specificity than Hamilton. Our results suggest that Hamilton may underdiagnose cases of major depressive episodes (MDE) as defined by DSM-V among black and low-income mothers compared with CES-D. In addition, we identify items in CES-D, which do not contribute to alignment with DSM-V and are appropriate targets for future improvements. Our analysis identifies interpersonal relationships and mother's age as the primary risk factors, which differentiate between CES-D and Hamilton determinations versus MDE diagnosis. In addition, we find regional differences in CES-D and Hamilton.
It is important to tailor the measure to the context, and a calibration sample should be considered for studies of sufficient size.
对抑郁症状进行充分评估是减少与收入相关的心理健康治疗不平等现象的必要步骤。尚无研究聚焦于比较用于检测低收入背景且育有幼儿的女性(这一时期抑郁症状风险增加)抑郁情况的工具。
为填补这一空白,在一个由251名低收入背景且孩子年龄在1至54个月的母亲组成的样本中,将两种常用工具(流行病学研究中心抑郁量表[CES-D]和汉密尔顿抑郁评定量表[Hamilton])与抑郁诊断(《精神疾病诊断与统计手册》第五版[DSM-V])进行比较。根据与母亲抑郁症状相关的背景因素对诊断效用进行检验。
在该样本中,CES-D的筛查敏感性和特异性优于Hamilton。我们的结果表明,与CES-D相比,Hamilton可能会对黑人及低收入母亲中由DSM-V定义的重度抑郁发作(MDE)病例漏诊。此外,我们确定了CES-D中与DSM-V不一致且是未来改进合适目标的项目。我们的分析确定人际关系和母亲年龄是区分CES-D和Hamilton判定与MDE诊断的主要风险因素。此外,我们发现CES-D和Hamilton存在地区差异。
根据具体情况调整测量方法很重要,对于规模足够大的研究应考虑使用校准样本。