双能量CT：头颈部癌评估中碘衰减与伪影减少之间的平衡
Dual-Energy CT: Balance Between Iodine Attenuation and Artifact Reduction for the Evaluation of Head and Neck Cancer.
作者信息
Nair Jaykumar R, DeBlois François, Ong Thomas, Devic Slobodan, Tomic Nada, Bekerat Hamed, Rosenbloom Lorne, Sultanem Khalil, Forghani Reza
机构信息
From the *Department of Radiology, †Division of Radiation Oncology and Medical Physics, ‡Segal Cancer Centre, §Lady Davis Institute for Medical Research, and ∥Department of Oncology, Division of Radiation Oncology, Jewish General Hospital, McGill University, Montreal, Quebec, Canada H3T 1E2.
出版信息
J Comput Assist Tomogr. 2017 Nov/Dec;41(6):931-936. doi: 10.1097/RCT.0000000000000617.
OBJECTIVE
Dual-energy computed tomography high energy virtual monochromatic images (VMIs) can reduce artifact but suppress iodine attenuation in enhancing tumor. We investigated this trade-off to identify VMI(s) that strike the best balance between iodine detection and artifact reduction.
METHODS
The study was performed using an Alderson radiation therapy phantom. Different iodine solutions (based on estimated tumor iodine content in situ using dual-energy computed tomography material decomposition) and different dental fillings were investigated. Spectral attenuation curves and quality index (QI: 1/SD) were evaluated.
RESULTS
The relationship between iodine attenuation and QI depends on artifact severity and iodine concentration. For low to average concentration solutions degraded by mild to moderate artifact, the iodine attenuation and QI curves crossed at 95 keV.
CONCLUSIONS
High energy VMIs less than 100 keV can achieve modest artifact reduction while preserving sufficient iodine attenuation and could represent a useful additional reconstruction for evaluation of head and neck cancer.
目的
双能计算机断层扫描高能虚拟单色图像（VMIs）可减少伪影，但会抑制强化肿瘤中的碘衰减。我们研究了这种权衡，以确定在碘检测和伪影减少之间达到最佳平衡的虚拟单色图像。
方法
使用Alderson放射治疗体模进行研究。研究了不同的碘溶液（基于使用双能计算机断层扫描物质分解原位估计的肿瘤碘含量）和不同的牙科填充物。评估了光谱衰减曲线和质量指数（QI：1/标准差）。
结果
碘衰减与质量指数之间的关系取决于伪影严重程度和碘浓度。对于由轻度至中度伪影降解的低至中等浓度溶液，碘衰减曲线和质量指数曲线在95keV处相交。
结论
能量低于100keV的高能虚拟单色图像在减少伪影的同时可保留足够的碘衰减，可能是评估头颈癌的一种有用的额外重建方法。
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