通过甘氨酸镍（II）简单便捷的三组分缩合反应实现碱促进的β-取代色氨酸的合成。
Base-Promoted Synthesis of β-Substituted-Tryptophans via a Simple and Convenient Three-Component Condensation of Nickel(II) Glycinate.
作者信息
Zhou Rui, Pan Zhaoping, Zhang Yuehua, Wu Fengbo, Jiang Qinglin, Guo Li
机构信息
West China School of Pharmacy, Sichuan University, Chengdu 610041, Sichuan, China.
Department of Medicinal Chemistry, School of Pharmacy, Chengdu Medical College, Chengdu 610500, Sichuan, China.
出版信息
Molecules. 2017 Apr 27;22(5):695. doi: 10.3390/molecules22050695.
Abstract
A three-component reaction of nickel(II) glycinate was conducted for the convenient synthesis of β-substituted-tryptophans. The reaction worked smoothly under mild conditions and the procedure was simple and easy to handle.
摘要
进行了甘氨酸镍（II）的三组分反应，以方便地合成β-取代色氨酸。该反应在温和条件下顺利进行，且步骤简单，易于操作。
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