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关于使用基于透明质酸的填充物进行年轻化治疗后预防和处理不良反应的共识声明。

Consensus statement on prevention and management of adverse effects following rejuvenation procedures with hyaluronic acid-based fillers.

机构信息

Hautzentrum Köln (Cologne Dermatology), Köln, Germany.

Sommerclinics, Frankfurt am Main, Germany.

出版信息

J Eur Acad Dermatol Venereol. 2017 Jul;31(7):1088-1095. doi: 10.1111/jdv.14295. Epub 2017 Jun 15.

DOI:10.1111/jdv.14295
PMID:28449190
Abstract

Facial fillers play an important role in the correction of facial changes associated with ageing. They offer quick treatments in the outpatient setting with minimal subsequent downtime that provide predictable, natural-looking, long-lasting results. Adverse reactions after hyaluronic acid injections tend to be mild or moderate and rather temporary. However, as with all injected or implanted biomaterials, severe adverse events can occur and patients must be fully informed of potential risks prior to undergoing treatment. A panel of experts from Germany (D), Austria (A) and Switzerland (CH) developed recommendations, and this study provides the 'DACH Consensus Recommendations' from this group specifically on the use of hyaluronic acid fillers. The aim is to help clinicians recognize potential risks and to provide guidance on how best to treat adverse events if they arise. Contraindications to hyaluronic acid fillers are also detailed, and ways to prevent adverse events occurring are discussed. Hyaluronic acid-based products are claimed to be very close to an ideal tissue augmentation agent; nevertheless, profound medical, anatomical and product knowledge are of paramount importance to minimize the occurrence of adverse reactions.

摘要

面部填充物在矫正与衰老相关的面部变化方面发挥着重要作用。它们在门诊环境下提供快速治疗,随后的恢复期很短,可带来可预测、自然且持久的效果。透明质酸注射后的不良反应往往是轻微或中度的,且较为短暂。然而,与所有注射或植入的生物材料一样,严重的不良事件也可能发生,因此患者在接受治疗前必须充分了解潜在风险。来自德国(D)、奥地利(A)和瑞士(CH)的一组专家制定了相关建议,本研究提供了该专家组专门针对透明质酸填充物使用的“DACH 共识建议”。其目的是帮助临床医生识别潜在风险,并在出现不良反应时提供最佳治疗指导。本文还详细介绍了透明质酸填充物的禁忌证,并讨论了预防不良反应发生的方法。尽管基于透明质酸的产品被认为非常接近理想的组织填充剂,但深入的医学、解剖学和产品知识对于最大限度地减少不良反应的发生至关重要。

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Real-World Evidence on the Routine Use, Efficacy, and Safety of a Hyaluronic Acid-Based Dermal Filler in the Periorbital Region.基于透明质酸的真皮填充剂在眶周区域常规使用、疗效及安全性的真实世界证据。
Aesthetic Plast Surg. 2025 May 29. doi: 10.1007/s00266-025-04809-9.
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Plast Reconstr Surg Glob Open. 2025 May 27;13(5):e6792. doi: 10.1097/GOX.0000000000006792. eCollection 2025 May.
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J Cosmet Dermatol. 2025 Apr;24(4):e70166. doi: 10.1111/jocd.70166.
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