经皮穴位电刺激（TEAS）可改善肺癌患者化疗引起的骨髓抑制。
Transcutaneous electrical acupoint stimulation (TEAS) ameliorates chemotherapy-induced bone marrow suppression in lung cancer patients.
作者信息
Hou Lili, Gu Fen, Gao Guanghui, Zhou Caicun
机构信息
Department of Nursing, Shanghai Pulmonary Hospital of Tongji University, Shanghai 200043, China.
Respiratory Department, Shanghai Pulmonary Hospital of Tongji University, Shanghai 200043, China.
出版信息
J Thorac Dis. 2017 Mar;9(3):809-817. doi: 10.21037/jtd.2017.03.12.
BACKGROUND
To investigate the effect of percutaneous electrical stimulation on chemotherapy-induced bone marrow suppression in patients with lung cancer.
METHODS
From December 2014 to August 2015, one hundred ninety-one non-small cell lung cancer patients with chemotherapy naive were randomly divided into control group, medication group, and transcutaneous electrical acupoint stimulation (TEAS) group. Patients with the control group received routine nursing care, the medication group was treated by oral administration of prophylactic agents, and TEAS group received electrical stimulation of acupoints including Dazhui (DU14), Geshu (BL17), Zusanli (ST36), Sanyinjiao (SP6), and Hegu (LI4). The primary end point was the blood routine indexes and secondary end point was the degree of comfort.
RESULTS
The white blood cell in the TEAS group was significantly higher than the control group on day 8 and day 14 (P<0.05). The platelet count in the TEAS group was significantly higher than control group on day 5, day 8 and day 11 (P<0.05). The comfort score in the TEAS group was significantly higher than control group on day 8 (P<0.05).
CONCLUSIONS
Percutaneous electrical stimulation of acupoints could prevent chemotherapy-induced bone marrow suppression in lung cancer patients and ensure a smooth continuation of chemotherapy.
背景
探讨经皮电刺激对肺癌患者化疗所致骨髓抑制的影响。
方法
2014年12月至2015年8月，将191例初治的非小细胞肺癌患者随机分为对照组、药物组和经皮穴位电刺激（TEAS）组。对照组患者接受常规护理，药物组口服预防性药物治疗，TEAS组接受对大椎（DU14）、膈俞（BL17）、足三里（ST36）、三阴交（SP6）和合谷（LI4）等穴位的电刺激。主要终点为血常规指标，次要终点为舒适度。
结果
TEAS组在第8天和第14天的白细胞计数显著高于对照组（P<0.05）。TEAS组在第5天、第8天和第11天的血小板计数显著高于对照组（P<0.05）。TEAS组在第8天的舒适度评分显著高于对照组（P<0.05）。
结论
经皮穴位电刺激可预防肺癌患者化疗所致的骨髓抑制，并确保化疗顺利持续进行。
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