Zhang Qu-Fei, Li Li-Xia, Lin Guo-Hua, Lin Li-Zhu
Guangzhou Hospital of TCM, Guangzhou 510130, Guangdong Province, China.
Zhongguo Zhen Jiu. 2013 Mar;33(3):207-10.
To observe the effect of direct moxibustion at Sihua points on immune function and life quality of chemotherapy patients with non-small cell lung cancer.
Eighty cases were randomly divided into a chemotherapy and moxibustion group (group A) and a chemotherapy group (group B), 40 cases in each one. Navelbine and cisplatin were applied in both groups. In addition, direct moxibustion at Sihua points which included Geshu (BL 17) and Danshu (BL 19) was used in the group A. Three moxa-cones were given on each acupoint, once a day, ten days treatment made one session and totally one session was required. The change of colony stimulating factor (CSF), tumor necrosis factor (TNF), interleukin-2 (IL- 2) and Karnofsky scale was compared between the two groups before and after treatment.
After the treatment, the levels of serum CSF, IL-2 in the group A were higher than those in the group B (both P < 0.01), while the level of TNF in the group A was lower than that in the group B (P<0. 01). Although Karnofsky score was decreased in the two groups (both P < 0.01), the score in the group A was higher than that in the group B (P < 0.01).
Direct moxibustion at Sihua points could increase the levels of CSF and IL-2 and reduce TNF in the chemotherapy patients with lung cancer, which could improve immune function, clinical efficacy and life quality.
观察四花穴直接灸对非小细胞肺癌化疗患者免疫功能及生活质量的影响。
将80例患者随机分为化疗艾灸组（A组）和化疗组（B组），每组40例。两组均应用诺维本和顺铂。此外，A组采用四花穴（包括膈俞穴和胆俞穴）直接灸，每穴灸3壮，每日1次，10天为1个疗程，共治疗1个疗程。比较两组治疗前后集落刺激因子（CSF）、肿瘤坏死因子（TNF）、白细胞介素-2（IL-2）水平及卡氏评分的变化。
治疗后，A组血清CSF、IL-2水平高于B组（均P<0.01），而A组TNF水平低于B组（P<0.01）。两组卡氏评分均降低（均P<0.01），但A组评分高于B组（P<0.01）。
四花穴直接灸可提高肺癌化疗患者的CSF、IL-2水平，降低TNF水平，从而改善免疫功能、临床疗效及生活质量。
