聚甲基丙烯酸羟乙酯水凝胶结构中脱水过程的纳米级观察

Nanoscale Observation of Dehydration Process in PHEMA Hydrogel Structure.

作者信息

Chamerski Kordian, Korzekwa Witold, Filipecki Jacek, Shpotyuk Olha, Stopa Marcin, Jeleń Piotr, Sitarz Maciej

机构信息

Institute of Physics, Faculty of Mathematics and Natural Science, Jan Dlugosz University in Czestochowa, Al. Armii Krajowej 13/15, 42-200, Czestochowa, Poland.

Komed Clinic, Sobieskiego 54, 42-200, Czestochowa, Poland.

出版信息

Nanoscale Res Lett. 2017 Dec;12(1):303. doi: 10.1186/s11671-017-2055-3. Epub 2017 Apr 26.

DOI:10.1186/s11671-017-2055-3

PMID:28449541

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5406318/

Abstract

One of the most important field of interest in respect to hydrogel materials is their capability to water storage. The problem mentioned above plays an important role regarding to diffusion of fluid media containing nanoparticles, what is very useful in biomedical applications, such as artificial polymeric implants, drug delivery systems or tissue engineering.In presented work, dehydration process in hydrogels used in ophthalmology as intraocular lenses was observed. Before measurements studied materials were immersed in deionized water and saline solution to obtain equilibrium swelling state. Studies of the dehydration process were carried out by use of gravimetric analysis, Fourier-Transform Infrared and Positron Annihilation Lifetime Spectroscopy. Obtained results revealed changes in hydrogen bonding structure and free volume holes induced by saline solution ingredients.

摘要

关于水凝胶材料，最重要的研究领域之一是它们的储水能力。上述问题在含纳米颗粒的流体介质扩散方面起着重要作用，这在生物医学应用中非常有用，例如人工聚合物植入物、药物递送系统或组织工程。在本研究中，观察了眼科中用作人工晶状体的水凝胶的脱水过程。在测量之前，将研究材料浸入去离子水和盐溶液中以获得平衡溶胀状态。通过重量分析、傅里叶变换红外光谱和正电子湮没寿命谱对脱水过程进行了研究。所得结果揭示了盐溶液成分引起的氢键结构和自由体积空穴的变化。