Kim Su Jin, Kim Hyo Yeol, Jeong Jong In, Hong Sang Duk, Chung Seung-Kyu, Dhong Hun-Jong
Department of Otorhinolaryngology, Eulji University Hospital, Eulji University School of Medicine, Daejeon, Korea.
Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Clin Exp Otorhinolaryngol. 2017 Sep;10(3):259-264. doi: 10.21053/ceo.2017.00052. Epub 2017 Apr 28.
This study evaluated whether the symptoms of laryngopharyngeal reflux (LPR) change after multilevel surgery for obstructive sleep apnea (OSA).
Patients who underwent multilevel surgery for OSA between April 2009 and September 2014 were enrolled in this study. All patients underwent preoperative polysomnography prior to surgery and were asked to complete the reflux symptom index (RSI) questionnaire before and after surgery.
Of 73 enrolled patients, 24 (33%) reported an RSI score >13 and were thus classified as having reflux. The mean RSI score before surgery was 11.48±7.95; this number decreased to 4.95±6.19 after surgery (<0.001). The rate of positive RSI responses was 33% before surgery and 9% after surgery. Each variable that comprised the RSI improved significantly after surgery, except for difficulty with swallowing. Regarding the degree of RSI improvement after surgery, there were no significant differences between subgroups according to sex, age, body mass index, OSA severity, or surgical outcome.
LPR symptoms are prevalent in OSA patients. Treatment for OSA using multilevel surgery potentially reduces the symptoms of LPR.
本研究评估阻塞性睡眠呼吸暂停(OSA)多级手术后喉咽反流(LPR)症状是否改变。
纳入2009年4月至2014年9月间接受OSA多级手术的患者。所有患者在手术前均接受术前多导睡眠图检查,并被要求在手术前后完成反流症状指数(RSI)问卷。
73名纳入患者中,24名(33%)报告RSI评分>13,因此被归类为有反流。手术前RSI平均评分为11.48±7.95;手术后降至4.95±6.19(<0.001)。手术前RSI阳性反应率为33%,手术后为9%。构成RSI的每个变量在手术后均有显著改善,但吞咽困难除外。关于手术后RSI改善程度,根据性别、年龄、体重指数、OSA严重程度或手术结果划分的亚组之间无显著差异。
LPR症状在OSA患者中普遍存在。采用多级手术治疗OSA可能会减轻LPR症状。