眼眶的CD34 +肿瘤，包括孤立性纤维性肿瘤：6例病例系列
CD34 + tumours of the orbit including solitary fibrous tumours: a six-case series.
作者信息
Jung Su Kyung, Paik Ji Sun, Park Gyeong Sin, Yang Suk-Woo
机构信息
Eye clinic, Hospital, National Cancer center, Gyeonggi-do, Korea.
Department of Ophthalmology and Visual Science, College of Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, 505 Banpo-dong, Seocho-gu, Seoul, 137-701, Korea.
出版信息
BMC Ophthalmol. 2017 Apr 27;17(1):59. doi: 10.1186/s12886-017-0455-x.
BACKGROUND
To report six cases of CD34+ fibroblastic mesenchymal tumours, which are uncommon neoplasms in the orbit.
CASE PRESENTATION
Six patients presenting with proptosis and palpable mass who were later diagnosed with fibrous solitary tumours, fibrous histocytoma or haemangiopericytoma in the orbit were included. All patients received radiologic examinations and surgical excision for histopathology and immunohistochemistry examinations. Five patients had no recurrence after a minimum follow-up of 12 months. One patient (case 6) experienced recurrence twice, and had debulking surgeries each time. At present, the patient still has remnant tumour in the orbit, but no growth has been detected during the past two years. The tumour size will be closely monitored.
CONCLUSIONS
Even though fibroblastic tumours are rarely found in the orbit, they can present as a palpable mass with proptosis. Complete surgical excision is important for long-term prognosis, and immunohistochemical study is helpful for confirming pathologic diagnosis.
背景
报告6例CD34+纤维母细胞性间叶肿瘤，这是眼眶中罕见的肿瘤。
病例报告
纳入6例出现眼球突出和可触及肿块的患者，这些患者后来被诊断为眼眶纤维性孤立性肿瘤、纤维组织细胞瘤或血管外皮细胞瘤。所有患者均接受了放射学检查及手术切除，以进行组织病理学和免疫组织化学检查。5例患者在至少随访12个月后无复发。1例患者（病例6）复发两次，每次均进行了减瘤手术。目前，该患者眼眶内仍有残留肿瘤，但在过去两年中未发现生长。将密切监测肿瘤大小。
结论
尽管纤维母细胞性肿瘤在眼眶中很少见，但可表现为伴有眼球突出的可触及肿块。完整的手术切除对长期预后很重要，免疫组织化学研究有助于确诊病理诊断。
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